标签归档：ym

2045-1   YM201636   品牌 Biovision

发表于由

YM201636

货号： 2045-1      产品名称： YM201636   品牌： Biovision 规格： 1 mg 3周到货 生化实验

YM201636
A PIKfyve inhibitor
Product Overview
Product Name: YM201636
Alternate Name/Synonyms: 6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3′2′:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridine carboxamide
Description: Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC50 = 33 nM). It inhibits p110α at higher concentration (IC50 = 3 µM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA.YM-201636 also blocks retroviral exit by budding from cells.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 371942-69-7
Molecular Formula: C₂₅H₂₁N₇O₃
Molecular Weight: 467.49
Purity: ≥98% by NMR
Solubility:DMSO or EtOH
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
InChi: InChI=1S/C25H21N7O3/c26-19-7-6-16(14-28-19)24(33)29-17-4-1-3-15(13-17)22-30-20-18-5-2-8-27-25(18)35-21(20)23(31-22)32-9-11-34-12-10-32/h1-8,13-14H,9-12H2,(H2,26,28)(H,29,33)
InChi Key: YBPIBGNBHHGLEB-UHFFFAOYSA-N
PubChem CID: 9956222
MDL Number: MFCD16038303
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

2045-5   YM201636   品牌 Biovision

发表于由

YM201636

货号： 2045-5      产品名称： YM201636   品牌： Biovision 规格： 5 mg 3周到货 生化实验

YM201636
A PIKfyve inhibitor
Product Overview
Product Name: YM201636
Alternate Name/Synonyms: 6-Amino-N-(3-(4-(4-morpholinyl)pyrido[3′2′:4,5]furo[3,2-d]pyrimidin-2-yl)phenyl)-3-pyridine carboxamide
Description: Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC50 = 33 nM). It inhibits p110α at higher concentration (IC50 = 3 µM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA.YM-201636 also blocks retroviral exit by budding from cells.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 371942-69-7
Molecular Formula: C₂₅H₂₁N₇O₃
Molecular Weight: 467.49
Purity: ≥98% by NMR
Solubility:DMSO or EtOH
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
InChi: InChI=1S/C25H21N7O3/c26-19-7-6-16(14-28-19)24(33)29-17-4-1-3-15(13-17)22-30-20-18-5-2-8-27-25(18)35-21(20)23(31-22)32-9-11-34-12-10-32/h1-8,13-14H,9-12H2,(H2,26,28)(H,29,33)
InChi Key: YBPIBGNBHHGLEB-UHFFFAOYSA-N
PubChem CID: 9956222
MDL Number: MFCD16038303
USAGE: For Research Use Only! Not For Use in Humans.

-20°C