未-Tocotrienol

货号： 10008513-25      产品名称： 未-Tocotrienol   品牌： Cayman 规格： 25 mg 3周

δ-Tocotrienol
Cayman Chemical Item Number 10008513
Description
The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1↗ Tocotrienols are found in high concentrations in palm oil and rice bran. Recent studies observe that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2↗ At 0.1-10 µM, δ-tocotrienol significantly suppresses H2O2-induced cell death of rat striatal neurons and provides protection against S-nitrocysteine-induced cell death and SIN-1 cytotoxicity in a concentration dependant manner.2↗ At concentrations of 10 µM, δ-tocotrienol displays more inhibitory action on adhesiveness of HAECs to U937 monocytic cells, via inhibition of VCAM-1 expression, than α-tocopherol and other tocotrienols at the same concentration.3↗
Formal Name 3,​4-​dihydro-​2,​8-​dimethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl]-​2H-​1-​benzopyran-​6-​ol
CAS Number 25612-59-3
Molecular Formula C27H40O2
Formula Weight 396.6
Formulation A solution in ethanol
Purity ≥98%
λmax 298 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES C/C(CC/C=C(C)​/CC/C=C(C)​/C)​=CCC[C@@]​1(C)​OC2=C(C)​C=C(O)​C=C2CC1 
InCHI Code 1S/C27H40O2/c1-20(2)​10-7-11-21(3)​12-8-13-22(4)​14-9-16-27(6)​17-15-24-19-25(28)​18-23(5)​26(24)​29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1 
InCHI Key ODADKLYLWWCHNB-LDYBVBFYSA-N

-20°C

纬-Tocotrienol

货号： 10008494-25      产品名称： 纬-Tocotrienol   品牌： Cayman 规格： 25 mg 3周

γ-Tocotrienol
Cayman Chemical Item Number 10008494
Description
The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1↗ Tocotrienols are found in high concentrations in palm oil and rice bran. Recent studies observe that tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2↗ Spontaneously hypertensive rats fed a diet which includes γ-tocotrienol show significant reduction of systolic blood pressure and an increase of nitric oxide synthase activity in blood vessels.3↗ γ-Tocotrienol at 20 µM induces apoptosis of malignant sympathoadrenal (+SA) murine mammary epithelial cells.4↗
Formal Name
3,​4-​dihydro-​2,​7,​8-​trimethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl]-​2H-​1-​benzopyran-​6-​ol
CAS Number 14101-61-2
Molecular Formula C28H42O2
Formula Weight 410.6
Formulation A solution in ethanol
Purity ≥98%
λmax 297 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES C[C@]​1(CC/C=C(C)​/CC/C=C(C)​/CC/C=C(C)​/C)​OC2=C(C)​C(C)​=C(O)​C=C2CC1 
InCHI Code 1S/C28H42O2/c1-20(2)​11-8-12-21(3)​13-9-14-22(4)​15-10-17-28(7)​18-16-25-19-26(29)​23(5)​24(6)​27(25)​30-28/h11,13,15,19,29H,8-10,12,14,16-18H2,1-7H3/b21-13+,22-15+/t28-/m1/s1 
InCHI Key OTXNTMVVOOBZCV-WAZJVIJMSA-N

-20°C

伪-Tocotrienol

货号： 10008377-25      产品名称： 伪-Tocotrienol   品牌： Cayman 规格： 25 mg 3周

α-Tocotrienol
Cayman Chemical Item Number 10008377
Description
The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1↗ Tocotrienols are found at high concentrations in palm oil and rice bran. Recent studies show tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2↗ Compared to other tocotrienols, α-tocotrienol exhibits the most potent neuroprotective actions in rat striatal neurons. At concentrations of 0.1-10 µM, α-tocotrienol significantly suppresses H2O2-induced cell death and provides protection against S-nitrocysteine-induced cell death and SIN-1 toxicity in a concentration dependent manner.2↗ HT4 cells, that are microinjected with 10−19 mol of α-tocotrienol into the cytosolic, are protected against glutamate-induced cell death by suppressing early activation of c-Src kinase and 12-lipoxygenase.3↗
Formal Name 3,​4-​dihydro-​2,​5,​7,​8-​tetramethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl)]-​2H-​1-​benzopyran-​6-​ol
CAS Number 58864-81-6
Molecular Formula C29H44O2
Formula Weight 424.7
Formulation A solution in ethanol
Purity ≥98%
λmax 289 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES C[C@]​1(CC/C=C(C)​/CC/C=C(C)​/CC/C=C(C)​/C)​OC2=C(C)​C(C)​=C(O)​C(C)​=C2CC1
InCHI Code ​1S/C29H44O2/c1-20(2)​12-9-13-21(3)​14-10-15-22(4)​16-11-18-29(8)​19-17-26-25(7)​27(30)​23(5)​24(6)​28(26)​31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1 
InCHI Key RZFHLOLGZPDCHJ-XZXLULOTSA-N

-20°C