伪-Tocotrienol

货号： 10008377-25      产品名称： 伪-Tocotrienol   品牌： Cayman 规格： 25 mg 3周

α-Tocotrienol
Cayman Chemical Item Number 10008377
Description
The four tocopherols (α, β, δ, and γ) and four tocotrienols (α, β, δ, and γ) are forms of vitamin E, which is known for its antioxidant activity.1↗ Tocotrienols are found at high concentrations in palm oil and rice bran. Recent studies show tocotrienols may be more effective antioxidants than α-tocopherol, the most abundant form of vitamin E.2↗ Compared to other tocotrienols, α-tocotrienol exhibits the most potent neuroprotective actions in rat striatal neurons. At concentrations of 0.1-10 µM, α-tocotrienol significantly suppresses H2O2-induced cell death and provides protection against S-nitrocysteine-induced cell death and SIN-1 toxicity in a concentration dependent manner.2↗ HT4 cells, that are microinjected with 10−19 mol of α-tocotrienol into the cytosolic, are protected against glutamate-induced cell death by suppressing early activation of c-Src kinase and 12-lipoxygenase.3↗
Formal Name 3,​4-​dihydro-​2,​5,​7,​8-​tetramethyl-​2R-​[(3E,​7E)-​4,​8,​12-​trimethyl-​3,​7,​11-​tridecatrienyl)]-​2H-​1-​benzopyran-​6-​ol
CAS Number 58864-81-6
Molecular Formula C29H44O2
Formula Weight 424.7
Formulation A solution in ethanol
Purity ≥98%
λmax 289 nm
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES C[C@]​1(CC/C=C(C)​/CC/C=C(C)​/CC/C=C(C)​/C)​OC2=C(C)​C(C)​=C(O)​C(C)​=C2CC1
InCHI Code ​1S/C29H44O2/c1-20(2)​12-9-13-21(3)​14-10-15-22(4)​16-11-18-29(8)​19-17-26-25(7)​27(30)​23(5)​24(6)​28(26)​31-29/h12,14,16,30H,9-11,13,15,17-19H2,1-8H3/b21-14+,22-16+/t29-/m1/s1 
InCHI Key RZFHLOLGZPDCHJ-XZXLULOTSA-N

-20°C