PFKFB3 Inhibitor, 3PO
货号: 525330-25MG 产品名称: PFKFB3 Inhibitor, 3PO 品牌: Merck 规格: *** 3周到货 生化实验
PFKFB3 Inhibitor, 3PO
(2E)-3-Pyridin-3-yl-1-pyridin-4-ylprop-2-en-1-one, 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 Inhibitor, 3PO
A cell-permeable dipyridinyl-propenone compound that selectively blocks PFK-2 (6-phosphofructo-2-kinase) activity of PFKFB3 isozyme over PFK-1 (6-phosphofructo-1-kinase) in a mixed-mode manner. Rapidly decreases fructose-2,6-bisphosphate (F-2,6-P2) and 2-deoxyglucose uptake, and lactate secretion; efficiently arrests proliferation of transformed cells (IC50 ~ 1.4 µM in NHBE-ht/LT/ras) and suppresses tumor growth in several xenograft mouse models (70 mg/kg, i.p.). The cytostatic and cytotoxic effects of 3PO is shown to be highly sensitive to the intracellular levels of F-6-P (fructose-6-phosphate) and F-2,6-P2.
产品信息
Form Pale yellow solid
Molar mass 210.2
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥99% by HPLC
Solubility DMSO
Chemical formula C13H10N2O
商店和运输信息
Storage +2°C to +8°C
Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling
2°C – 8°C
9012660 Cable, X-main to X-adapter, 20po, BR8000 品牌 Qiagen
Cable, X-main to X-adapter, 20po, BR8000
货号: 9012660 产品名称: Cable, X-main to X-adapter, 20po, BR8000 品牌: Qiagen 规格: ***
WBAVDP001 blok – PO Phosphoprotein Blocker, 500mL 品牌 Millipore
blok – PO Phosphoprotein Blocker, 500mL
货号: WBAVDP001 产品名称: blok – PO Phosphoprotein Blocker, 500mL 品牌: Millipore 规格: EA
4310879E FG,PDAR HUMAN PO 品牌 Invitrogen
FG,PDAR HUMAN PO
货号: 4310879E 产品名称: FG,PDAR HUMAN PO 品牌: Invitrogen 规格: EACH 三周到货 生化试验
Human RPLP0 (Large Ribosomal Protein) Endogenous Control (VIC®/TAMRA™ probe, primer limited)
The Applied Biosystems® Human RPLP0 (large ribosomal protein) Endogenous Control (VIC® ⁄ TAMRA Probe, Primer Limited) is intended as an endogenous control. It allows relative gene expression quantification in cDNA samples when used with other TaqMan® gene expression assays. Probe is labeled with VIC™ dye – TAMRA™ dye and the primers are limited. Can be used for multiplex or singleplex PCR reactions. Endogenous control is to be used with Inventoried and Made to Order TaqMan® Gene Expression Assays, Custom TaqMan® Gene Expression Assays, and⁄or Custom TaqMan® Primers and Probes.
Assay Details:
Gene Symbol: RPLPO
RefSeq: NM_001002.3
Probe Exon Location: 3
Amplicon Size: 154
Format: Tube(s)
Species: Human
Includes: Control Primer-Probe Set(s)
Gene Symbol: RPLPO
Target Gene: RPLPO
Label or Dye: VIC®
Product Size: 2500 reactions
Amplicon Size: 154
Accession Number: NM_001002.3
Shipping Condition: Dry Ice
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Package includes 4 tubes containing 20X mix of pre-formulated assay (1 probe and 2 primers).
Store at -15 °C to -25 °C
4326314E FG,HU PO MGB 品牌 Invitrogen
FG,HU PO MGB
货号: 4326314E 产品名称: FG,HU PO MGB 品牌: Invitrogen 规格: EACH 三周到货 生化试验
Human RPLPO (Large Ribosomal Protein) Endogenous Control, VIC®/MGB probe, primer limited
Human RPLPO (Large Ribosomal Protein) Endogenous Control allows relative gene expression quantification in cDNA samples when used with other gene expression assays. The probe is labeled with VIC™ dye-MGB, and the primers are limited. It can be used for multiplex or singleplex PCR reactions. This endogenous control is designed to be used with TaqMan® gene expression assays or TaqMan® primers/probes.
Assay Details:
Gene Symbol: RPLPO
RefSeq: NM_001002.3
Probe Exon Location:3
Amplicon Size: 105
TaqMan® Endogenous Controls
Eliminate months of assay design, formulation, and testing by using TaqMan® endogenous controls to quantify gene expression. This convenient collection of pre-designed primer/probe sets enables you to normalize the amount of sample RNA or DNA in a reaction.
Complete Solution for Quantitative Gene Expression
Having a hard time deciding what controls to use to quantify gene expression—even with detailed information on biological systems Now, with TaqMan®
Format: Tube(s)
Species: Human
Includes: Control Primer-Probe Set(s)
Gene Symbol: RPLPO
Target Gene: RPLPO
Label or Dye: VIC®
Product Size: 2500 reactions
Amplicon Size: 105
Accession Number: NM_001002.3
Green Features: Less waste,
Sustainable packaging
Shipping Condition: Ambient
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Package includes 4 tubes containing 20X mix of pre-formulated assay (1 probe and 2 primers).
Store at -15°C to -25°C
20-382 GenoStat Ligand*PO* 品牌 Millipore
GenoStat Ligand*PO*
货号: 20-382 产品名称: GenoStat Ligand*PO* 品牌: Millipore 规格: EA
AB3920 RFXANK, RBX-50UG *PO* 品牌 Millipore
RFXANK, RBX-50UG *PO*
货号: AB3920 产品名称: RFXANK, RBX-50UG *PO* 品牌: Millipore 规格: EA
AB5760 LHX4, RBX-100UG *PO* 品牌 Millipore
LHX4, RBX-100UG *PO*
货号: AB5760 产品名称: LHX4, RBX-100UG *PO* 品牌: Millipore 规格: EA
AB5807 SOX-8, RBX-100UG *PO* 品牌 Millipore
SOX-8, RBX-100UG *PO*
货号: AB5807 产品名称: SOX-8, RBX-100UG *PO* 品牌: Millipore 规格: EA
AB9352 PO, CHKX-500UL 品牌 Millipore
PO, CHKX-500UL
货号: AB9352 产品名称: PO, CHKX-500UL 品牌: Millipore 规格: EA 三周到货 生化实验
Anti-Po Antibody
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PRODUCT FAMILY INFORMATION
Glial Cell Markers
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
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Species Reactivity Key Applications Host Format Antibody Type
H, M ICC, IHC Chicken Affinity Purified Polyclonal Antibody
Description:
Anti-Po Antibody
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Trade Name:
Chemicon (Millipore)
Specificity:
Recognizes Glycoprotein Po. Po is the major glycoprotein in peripheral myelin
Immunogen:
Synthetic peptides from human/mouse Po.
Species Reactivity:
Human
Mouse
Application Notes:
Immunohistochemistry: 1:50-1:100 using 2% paraformaldehyde fixed tissues.
Immunocytochemistry: 1:50-1:100 using 2% paraformaldehyde fixed cells.
Optimal working dilutions must be determined by the end user.
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Presentation:
Affinity purified chicken IgY. Two different antibodies were combined to make this product. Liquid in PBS, pH 7.2 with 0.02% sodium azide.
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. It is recommended that the antibody be stored in the dark.
UniProt Number:
P25189
Entrez Gene Number:
NP_000521.2
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Immunocytochemistry
Immunohistochemistry
Brand Family:
Chemicon
Product Name:
Anti-Po Antibody
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
500 µL
Format:
Affinity Purified
Host:
Chicken
Applications:
This Anti-Po Antibody is validated for use in IC, IH for the detection of Po.
2-8℃