标签归档：fatty

341326-5MG   Fatty Acid Synthase Inhibitor, Cpd 10v   品牌 Merck

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Fatty Acid Synthase Inhibitor, Cpd 10v

货号： 341326-5MG      产品名称： Fatty Acid Synthase Inhibitor, Cpd 10v   品牌： Merck 规格： *** 3周到货 生化实验

Fatty Acid Synthase Inhibitor, Cpd 10v
7-chloro-4-hydroxy-3-(2′-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor
A hydroxyquinolinone derivative that acts as a potent reversible inhibitor of type 1 fatty acid synthase (FAS) (IC50 = 19 nM) when enzyme activity is monitored by following the synthesis of free coenzyme A (CoA-SH).
产品信息
Form  White solid
Molar mass  402.83
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥98% by HPLC
Solubility  DMSO
Chemical formula  C23H15ClN2O3
CAS number  1027354-00-2
商店和运输信息
Storage  -20°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Regulatory Review

-20°C

10504-100   Fatty Acid Screening Library (96-Well)   品牌 Cayman

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Fatty Acid Screening Library (96-Well)

货号： 10504-100      产品名称： Fatty Acid Screening Library (96-Well)   品牌： Cayman 规格： 100 碌l 3周

Fatty Acid Screening Library (96-Well) Cayman Chemical Item Number 10504 Description The Fatty Acid Screening Library contains more than 75 compounds of fatty acids with diverse biological activities in a 96-well Matrix tube rack format as 2 mM stocks in DMSO. The library may also include some of the most commonly-ordered fatty acids, including arachidonic, linoleic, eicosapentaenoic, stearic, α- and γ-linolenic, oleic, and palmitic acids. As well as some unusual fatty acids, including 9-thiastearic acid, 2-hydroxymyristic acid, AUDA, and CUDA may be included. The composition of this screening library will always vary somewhat depending upon our inventory. Stability data is not available for compounds as supplied in the screening library. Formulation A 2 mM solution in DMSO Stability 2 years Storage -20°C Shipping Wet ice in continental US; may vary elsewhere -20°C

10504-200   Fatty Acid Screening Library (96-Well)   品牌 Cayman

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Fatty Acid Screening Library (96-Well)

货号： 10504-200      产品名称： Fatty Acid Screening Library (96-Well)   品牌： Cayman 规格： 200 碌l 3周

Fatty Acid Screening Library (96-Well) Cayman Chemical Item Number 10504 Description The Fatty Acid Screening Library contains more than 75 compounds of fatty acids with diverse biological activities in a 96-well Matrix tube rack format as 2 mM stocks in DMSO. The library may also include some of the most commonly-ordered fatty acids, including arachidonic, linoleic, eicosapentaenoic, stearic, α- and γ-linolenic, oleic, and palmitic acids. As well as some unusual fatty acids, including 9-thiastearic acid, 2-hydroxymyristic acid, AUDA, and CUDA may be included. The composition of this screening library will always vary somewhat depending upon our inventory. Stability data is not available for compounds as supplied in the screening library. Formulation A 2 mM solution in DMSO Stability 2 years Storage -20°C Shipping Wet ice in continental US; may vary elsewhere -20°C

10504-50   Fatty Acid Screening Library (96-Well)   品牌 Cayman

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Fatty Acid Screening Library (96-Well)

货号： 10504-50      产品名称： Fatty Acid Screening Library (96-Well)   品牌： Cayman 规格： 50 碌l 3周

Fatty Acid Screening Library (96-Well) Cayman Chemical Item Number 10504 Description The Fatty Acid Screening Library contains more than 75 compounds of fatty acids with diverse biological activities in a 96-well Matrix tube rack format as 2 mM stocks in DMSO. The library may also include some of the most commonly-ordered fatty acids, including arachidonic, linoleic, eicosapentaenoic, stearic, α- and γ-linolenic, oleic, and palmitic acids. As well as some unusual fatty acids, including 9-thiastearic acid, 2-hydroxymyristic acid, AUDA, and CUDA may be included. The composition of this screening library will always vary somewhat depending upon our inventory. Stability data is not available for compounds as supplied in the screening library. Formulation A 2 mM solution in DMSO Stability 2 years Storage -20°C Shipping Wet ice in continental US; may vary elsewhere -20°C

101600-1T   Fatty Acid Amide Hydrolase Polyclonal Antibody   品牌 Cayman

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Fatty Acid Amide Hydrolase Polyclonal Antibody

货号： 101600-1T      产品名称： Fatty Acid Amide Hydrolase Polyclonal Antibody   品牌： Cayman 规格： Trial 3周

Fatty Acid Amide Hydrolase Polyclonal Antibody Cayman Chemical Item Number 101600 Description Antigen: rat fatty acid amide hydrolase amino acids 561-579 conjugated to KLH · Host: rabbit · Application(s): WB · FAAH catalyzes the hydrolysis of biologically significant fatty acid amides.1↗ Characterization of FAAH, its substrates, and inhibitors have helped to partially elucidate molecular regulation of sleep,2↗ nociception,3↗,4↗ and cancer.5↗ FAAH is an intracellular enzyme linked to the plasma-membrane via its N-terminal domain.6↗,7↗ The purified enzyme from rat has an estimated molecular mass of 63,000.6↗ Cloning and characterization of porcine, mouse, and human FAAH indicate highly conserved homology with the rat sequence.8↗,9↗ Northern and immunoblot analyses reveals that FAAH exists in a wide variety of tissues and is particularly abundant in liver, pancreas, brain, testes, uterus, small intestine, and ocular tissue.10↗,1↗,7↗,9↗ Synonyms Anandamide Amidohydrolase,FAAH,Oleamide Hydrolase Formulation Peptide affinity-purified IgG Stability 1 year Storage -20°C Shipping Room temperature in continental US; may vary elsewhere Specificity Human FAAH,Ferret FAAH,Mouse FAAH -20°C

BML-2803-0100   Fatty Acid Library   品牌 Biomol

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Fatty Acid Library

货号： BML-2803-0100      产品名称： Fatty Acid Library   品牌： Biomol 规格： Pack 3周到货 生化试验

The Screen-Well™ Fatty Acid Library contains 68 fatty acids of varying saturation and chain length. Many free fatty acids and their metabolites serve as precursors to important signaling systems (e.g. prostaglandins), act directly as receptor ligands or enzyme inhibitors, and have pro- or anti-atherosclerotic and anti-hypertensive properties through mechanisms that are still being characterized. Therefore, a diverse set of fatty acids can be a rich source of compounds for receptor de-orphaning, inhibitor screening, and high content screening. Fatty acids are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 µl per well. This set contains both fatty acids with defined activities and fatty acids with putative biological activities.Library includes:Unsaturated & saturated fatty acids, Arachidonic acid, C10-24 chain length Linolenic acid, E and Z isomers, γ-Linolenic acid and many more.
Product Specification
Quantity: 20 assays  
Long Term Storage: -80°C

-80°C

BML-2803-0500   Fatty Acid Library   品牌 Biomol

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Fatty Acid Library

货号： BML-2803-0500      产品名称： Fatty Acid Library   品牌： Biomol 规格： Pack 3周到货 生化试验

The Screen-Well™ Nuclear Receptor Ligand Library contains 76 compounds with defined, putative and potential activity at nuclear receptors. Receptor agonists and antagonists are included. The library consists of a chemically diverse group of compounds which are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well, 96-well plates at 500 µl or 100 µl per well. The library is an ideal tool for chemical genomics, receptor de-orphaning and other routine pharmacological applications. The library includes ligands for the following classes of nuclear receptors: AHR, CAR, ER, FXR, LXR, PPAR, PXR, RAR, RXR, VDR, and other steroid receptors.
Product Specification
Long Term Storage: -80°C

-80°C

AB5644P   FATTY ACID AMIDE HYDRO, RBX-50UG   品牌 Millipore

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FATTY ACID AMIDE HYDRO, RBX-50UG

货号： AB5644P      产品名称： FATTY ACID AMIDE HYDRO, RBX-50UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Fatty Acid Amide Hydrolase Antibody
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REFERENCES
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease.
Cristina Blázquez,Anna Chiarlone,Onintza Sagredo,Tania Aguado,M Ruth Pazos,Eva Resel,Javier Palazuelos,Boris Julien,María Salazar,Christine Börner,Cristina Benito,Carolina Carrasco,María Diez-Zaera,Paola Paoletti,Miguel Díaz-Hernández,Carolina Ruiz,Michael Sendtner,José J Lucas,Justo G de Yébenes,Giovanni Marsicano,Krisztina Monory,Beat Lutz,Julián Romero,Jordi Alberch,Silvia Ginés,Jürgen Kraus,Javier Fernández-Ruiz,Ismael Galve-Roperh,Manuel Guzmán (2011) Brain : a journal of neurology.134
The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells.
Aguado, Tania, et al. (2006) J. Neurosci., 26: 1551-61 (2006)
The endocannabinoid system drives neural progenitor proliferation.
Aguado, Tania, et al. (2005) FASEB J., 19: 1704-6 (2005)
Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide.
Sherrye T Glaser, Dale G Deutsch, Keith M Studholme, Sarah Zimov, Stephen YazullaVisual neuroscience.22:693-705
Species Reactivity Key Applications Host Format Antibody Type
H, R  ELISA, WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Fatty Acid Amide Hydrolase Antibody
Promotional Text:
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Trade Name:
Chemicon (Millipore)
Specificity:
Recognizes human Fatty Acid Amide Hydrolase (FAAH). The immunogen shows no significant sequence homology with other hydrolases
SPECIES REACTIVITIES: The immunogen peptide is 100% conserved in rat, 94% in mouse and porcine and 58% in chicken. Reactivity with other species has not been confirmed.
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Immunogen:
A 17 amino acid peptide sequence near the N-terminus of human FAAH (Patricelli et al. 1998; Maccarone et al. 1998; Cravatt et al. 1996; Giang et al. 1997; Thomas et al. 1997; Wan et al. 1998).
Species Reactivity:
Human
Rat
Application Notes:
Western blot: 1-10 μg/mL using ECL.
ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide (Catalog Number AG376) per well.
Optimal working dilutions must be determined by the end user.
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Presentation:
Affinity purified immunoglobulin. Liquid in 100 mM Tris, pH 7.5, containing 0.2% BSA and 0.05% sodium azide.
Storage Conditions:
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
UniProt Number:
O00519
Alternate Names:
FAAH
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
ELISA
Western Blotting
Brand Family:
Chemicon
Product Name:
Anti-Fatty Acid Amide Hydrolase Antibody
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
50 µg
Format:
Affinity Purified
Host:
Rabbit
Applications:
This Anti-Fatty Acid Amide Hydrolase Antibody is validated for use in ELISA, WB for the detection of Fatty -20℃