标签归档：timp

PF019-3UG   TIMP-1, RECOMBINANT, HUMAN   品牌 Merck

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TIMP-1, RECOMBINANT, HUMAN

货号： PF019-3UG      产品名称： TIMP-1, RECOMBINANT, HUMAN   品牌： Merck 规格： 3UG 3周到货 生化实验

产品信息
Recombinant, human TIMP-1 expressed in CHO cells. Migrates as a 28 kDa protein under reducing conditions on SDS-PAGE.  
Form  Lyophilized 
Formulation  Lyophilized from ammonium bicarbonate, sodium chloride, sodium phosphate buffer, 100 µg BSA, pH 7.3. 
Primary Target  human MMP 1 
Primary Target IC50  1-5 nM 
Preservative  None 
Biological activity  IC50 against native human MMP-1 is ~1-5 nM. 
Purity  ≥95% by SDS PAGE (prior to lyophilization) 
Declaration  Manufactured by Daiichi Fine Chemical Co., Ltd. Not available for sale in Japan. 
Storage  -20°C 

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PF021-3UG   TIMP-2, HUMAN, RECOMBINANT   品牌 Merck

发表于由

TIMP-2, HUMAN, RECOMBINANT

货号： PF021-3UG      产品名称： TIMP-2, HUMAN, RECOMBINANT   品牌： Merck 规格： *** 3周到货 生化实验

TIMP-2, Human, Recombinant, CHC Cells
Tissue Inhibitor of Metalloproteinase 2
Recombinant, human TIMP-2 expressed in CHC cells. Migrates as a 24 kDa protein under reducing conditions on SDS-PAGE. Use 20 µl per gel lane. M. W.: 24000
产品信息
Form  Lyophilized
Formulation  Lyophilized from PBS, 100 µg BSA.
Primary Target  human MMP-1
Primary Target IC50  2-10 nM
Preservative  None
Molar mass  24000
Applications 
Immunoblotting (Western Blotting)
Biological activity  IC50 against native human MMP-1 is in the range of 2-10 nM
Purity  >98% by SDS-PAGE
Solubility  PBS
Declaration  Sold under license of U.S. Patents 5,595,885 and 5,698,671. Manufactured by Daiichi Fine Chemical Co., Ltd. Not available for sale in Japan.
商店和运输信息
Storage  -20°C
Ship  Dry Ice Only
Standard Handling

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QIA40-1EA   TIMP-2 ELISA KIT   品牌 Merck

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TIMP-2 ELISA KIT

货号： QIA40-1EA      产品名称： TIMP-2 ELISA KIT   品牌： Merck 规格： *** 3周到货 生化实验

TIMP-2 ELISA Kit
A sandwich ELISA based kit specific for human TIMP-2. A non-isotopic immunoassay for thein vitromeasurement of human TIMP-2 protein in tissue culture medium, serum, plasma and tissue lysates.
产品信息
Format  96-well plate
Form  96 Tests
Detection method  Colorimetric
Species reactivity  bovine, guinea pig, human, mouse, rabbit, rat
Protect from Light  是的
Avoid freeze/thaw  是的
Specificity  Recognizes human TIMP-2 protein including free TIMP-2 and TIMP-2 complexed with active MMP-1, active MMP-2, active MMP-3, active MMP-7, active MMP-8, or active MMP-9. Does not recognize TIMP-2 complexed with proMMP-2
Sensitivity  3 ng/ml
Assay range  8 – 128 ng/ml
Assay time  4.5 h
Sample type  Tissue culture medium, serum, plasma, and tissue lysates
Kit contains  96-Well Coated Plate, TIMP-2 Standard, HRP Conjugate, Assay Buffers, Color Reagent, Plate Sealers, and a user protocol.
Declaration  Not available for sale in Japan.
商店和运输信息
Storage  -20°C
Ship  Dry Ice Only
Multiple Toxicity Values, refer to MSDS

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QIA54-1EA   TIMP-1 ELISA KIT   品牌 Merck

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TIMP-1 ELISA KIT

货号： QIA54-1EA      产品名称： TIMP-1 ELISA KIT   品牌： Merck 规格： *** 3周到货 生化实验

TIMP-1 ELISA Kit
A sandwich ELISA based kit specific for human TIMP-1. A non-isotopic colorimetricin vitroassay for the measurement of human TIMP-1 protein in tissue culture media or serum.
产品信息
Format  96-well plate
Form  96 Tests
Detection method  Colorimetric
Species reactivity  human
Avoid freeze/thaw  是的
Specificity  human TIMP-1 protein
Sensitivity  9.6 pg/ml
Assay range  0.05 – 1.6 ng/ml
Assay time  2 h
Sample type  Tissue culture media and serum
Kit contains  96-Well Coated Plate, Human TIMP-1 Standard, Detector Antibody, Assay Buffers, Color Reagent, Stop Solution, Plate Cover, and a user protocol.
Declaration  Manufactured by Daiichi Fine Chemical Co., Ltd. Not available for sale in Japan.
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage  -20°C
Ship  Dry Ice Only
Multiple Toxicity Values, refer to MSDS

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7786-5   TIMP-1, human recombinant   品牌 Biovision

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TIMP-1, human recombinant

货号： 7786-5      产品名称： TIMP-1, human recombinant   品牌： Biovision 规格： 5 μg 3周到货 生化实验

TIMP-1, human recombinant
An inhibitor of MMPs
Product Overview
Alternate Name/Synonyms: TIMP-1, Tissue Inhibitor of Matrix Metalloproteinases – 1, TIMP, TIMP recombinani, TIMP protein, TIMP-1, TIMP-1 recombinani, TIMP-1 protein,  MMP inhibitor
Gene Symbol: TIMP1
Accession #: P01033
Gene ID: 7076
Source: Sf9 cells
Appearance: Liquid
Physical Form Description: In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl₂; 1 μM ZnCl₂; 0.05% Brij 35; 0,05% NaN₃
Molecular Weight: 28.0 kDa
Purity by SDS-PAGE: ≥92%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry Ice
Background Information: The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-egradingmetalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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7787-5   TIMP-1, human   品牌 Biovision

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TIMP-1, human

货号： 7787-5      产品名称： TIMP-1, human   品牌： Biovision 规格： 5 μg 3周到货 生化实验

TIMP-1, human neutrophil granulocytes
An inhibitor of MMPs
Product Overview
Alternate Name/Synonyms: TIMP-1, Tissue Inhibitor of Matrix Metalloproteinases – 1, TIMP, TIMP recombinani, TIMP protein, TIMP-1, TIMP-1 recombinani, TIMP-1 protein, MMP inhibitor
Gene Symbol: TIMP1
Accession #: P01033
Gene ID: 7076
Source: Human neutrophil granulocytes (Buffy Coat)
Appearance: Liquid
Physical Form Description: In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl₂; 1 μM ZnCl₂; 0.05% Brij 35; 0,05% NaN₃
Molecular Weight: 28.0 kDa
Purity by SDS-PAGE: ≥92%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry Ice
Background Information: The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-egradingmetalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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7788-5   TIMP-2, human   品牌 Biovision

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TIMP-2, human

货号： 7788-5      产品名称： TIMP-2, human   品牌： Biovision 规格： 5 μg 3周到货 生化实验

TIMP-2, human fibroblasts
An inhibitor of MMPs
Product Overview
Alternate Name/Synonyms: TIMP-2, Tissue Inhibitor of Matrix Metalloproteinases – 2, TIMP-2, Tissue Inhibitor of Matrix Metalloproteinases – 2, TIMP, TIMP recombinani, TIMP protein, TIMP-2, TIMP-2 recombinani, TIMP-2 protein,  MMP inhibitor
Gene Symbol: TIMP2
Accession #: P16035
Gene ID: 7077
Source: Isolated from human fibroblasts
Appearance: Liquid
Physical Form Description: In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl₂; 1 μM ZnCl₂; 0.05% Brij 35; 0,05% NaN₃
Molecular Weight: 21.0 kDa
Purity by SDS-PAGE: ≥90%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry Ice
Background Information: Glycoprotein that belongs to a family which takes part in the activation and regulation of the MMP-activity. Forms a non-covalent stoichiometric complex with latent and active MMP’s. Inhibits the activities of MMP-1, MMP-2, MMP-12 and transin
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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BML-SA374-0100   TIMP-2, pAb   品牌 Biomol

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TIMP-2, pAb

货号： BML-SA374-0100      产品名称： TIMP-2, pAb   品牌： Biomol 规格： 100 ug 3周到货 生化实验

TIMP-2, pAb
Product Specification
Alternative Name:Tissue inhibitor of matrix metalloproteinases 2
Host:Rabbit
Immunogen:Synthetic peptide corresponding to a portion of loop #3 of human TIMP-2 (tissue inhibitor of matrix metalloproteinases-2).
UniProt ID:P16035
Application:Western Blot (1:1000 – 1:5000)
Optimal conditions must be determined individually for each application.
Specificity:Recognizes human mouse, rat, bovine and pig TIMP-2.
Purity Detail:Affinity purified
Formulation:Liquid. In PBS containing 0.05% sodium azide and 50% glycerol.
Handling:Avoid freeze/thaw cycles.
Long Term Storage:-20°C
 

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BML-SA375-0100   TIMP-3 (human), pAb   品牌 Biomol

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TIMP-3 (human), pAb

货号： BML-SA375-0100      产品名称： TIMP-3 (human), pAb   品牌： Biomol 规格： 100 ug 3周到货 生化实验

TIMP-3 (human), pAb
Among the TIMPs, TIMP-3 is unique in its ability to inhibit TACE/ADAM17.
Product Specification
Alternative Name:Tissue inhibitor of matrix metalloproteinases 3
Host:Rabbit
Immunogen:Synthetic peptide corresponding to a portion of C-terminal human TIMP-3 (tissue inhibitor of matrix metalloproteinases-3).
UniProt ID:P35625
Application:ELISA
Immunohistochemistry
Immunoprecipitation
Western Blot
Specificity:Recognizes human TIMP-3.
Formulation:Liquid. In 50% glycerol.
Long Term Storage:-20°C

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BML-SA380-0100   TIMP-4, pAb   品牌 Biomol

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TIMP-4, pAb

货号： BML-SA380-0100      产品名称： TIMP-4, pAb   品牌： Biomol 规格： 100 ug 3周到货 生化实验

TIMP-4, pAb
Product Specification
Alternative Name:Tissue inhibitor of matrix metalloproteinases 4
Host:Rabbit
Immunogen:Synthetic peptide corresponding to a portion of C-terminal human TIMP-4 (tissue inhibitor of matrix metalloproteinases-4).
UniProt ID:Q99727
Application:Western Blot (1:1000 – 1:5000)
Optimal conditions must be determined individually for each application.
Specificity:Recognizes human, rat and rabbit TIMP-4.
Purity Detail:Affinity purified
Formulation:Liquid. In PBS containing 0.05% sodium azide and 50% glycerol.
Handling:Avoid freeze/thaw cycles.
Long Term Storage:-20°C

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BML-SE469-0005   TIMP-2 (human) (purified)   品牌 Biomol

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TIMP-2 (human) (purified)

货号： BML-SE469-0005      产品名称： TIMP-2 (human) (purified)   品牌： Biomol 规格： 5 ug 3周到货 生化实验

TIMP-2 (human fibroblasts), (purified)
MMP inhibitor
Product Specification
Alternative Name:Tissue inhibitor of metalloproteinases 2
MW:~ 22 kDa
Source:Isolated from human fibroblasts.
UniProt ID:P16035
Application:MMP or ADAM inhibitor in vitro7 or in tissue culture; positive control in antibody applications or reverse zymograms.
Long Term Storage:-80°C
Miscellaneous/General:TIMP-2 inhibits most MMPs, particularly MMP-2. It can also inhibit ADAMs such as ADAMTS4.

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BML-SE530-0005   TIMP-1 (human) (purified)   品牌 Biomol

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TIMP-1 (human) (purified)

货号： BML-SE530-0005      产品名称： TIMP-1 (human) (purified)   品牌： Biomol 规格： 5 ug 3周到货 生化实验

DPPIII (human), (recombinant)
Product Specification
Alternative Name:Dipeptidyl Peptidase III, DPP3
MW:109 kDa
Source:Produced in insect cells. Active recombinant human DPPIII with an N-terminal purification tag.
UniProt ID:Q9NY33
Application:Study of enzyme kinetics, cleave target substrates, and screen for inhibitors.
Long Term Storage:-80°C
Miscellaneous/General:DPPIII is a metalloproteinase that cleaves biologically active peptides such as enkephalins, angiotensins, and endomorphins, and has beenDPPIII (human), (recombinant)
Product Specification
Alternative Name:Dipeptidyl Peptidase III, DPP3
MW:109 kDa
Source:Produced in insect cells. Active recombinant human DPPIII with an N-terminal purification tag.
UniProt ID:Q9NY33
Application:Study of enzyme kinetics, cleave target substrates, and screen for inhibitors.
Long Term Storage:-80°C
Miscellaneous/General:DPPIII is a metalloproteinase that cleaves biologically active peptides such as enkephalins, angiotensins, and endomorphins, and has been implicated in cancer, pain, and inflammation.TIMP-1 (human neutrophils), (purified)
MMP inhibitor
Product Specification
Alternative Name:Tissue inhibitor of metalloproteinases 1
Source:Isolated from human neutrophils.
UniProt ID:P01033
Application:MMP or ADAM inhibitor in vitro or in tissue culture; positive control in antibody applications or reverse zymograms.
Long Term Storage:-20°C
Miscellaneous/General:TIMP-1 inhibits most MMPs, displaying ki’s in the low nanomolar range, although it is not very effective against the MT-MMPs. It also can inhibit ADAMs such as ADAM10 and ADAMTS4. While it can inhibit angiogenesis, it can also promote cell growth. implicated in cancer, pain, and inflammation.

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BML-SW121-0100   TIMP-1, -2, -3, -4 Immunoblotting Standard (human)   品牌 Biomol

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TIMP-1, -2, -3, -4 Immunoblotting Standard (human)

货号： BML-SW121-0100      产品名称： TIMP-1, -2, -3, -4 Immunoblotting Standard (human)   品牌： Biomol 规格： 100 ul 3周到货 生化实验

TIMP-1, -2, -3, -4 immunoblotting standard (human)
Concentrated cell-conditioned serum-free medium, from PMA-stimulated HeLa cells, containing variable levels of human TIMP-1, TIMP-2, TIMP-3 and TIMP-4.
Product Specification
Formulation: Liquid. Concentrated cell-conditioned serum-free medium in SDS-PAGE sample buffer.
Application: Useful as a positive control for immunoblotting. Note: Boil sample before loading in gel. Suggested starting volume of BML-SW121 for gel loading: 8-10 µl.
Long Term Storage: -80°C
Handling: Avoid freeze/thaw cycles.

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