Anti-SCA-1

货号： AB4336      产品名称： Anti-SCA-1   品牌： Millipore 规格： *** 三周到货 生化实验

Anti-SCA-1
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Species Reactivity Key Applications Host Format Antibody Type
M, R  WB, ICC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-SCA-1 Antibody
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Specificity:
This antibody recognizes SCA-1 at the UPAR/Ly6 domain.
Molecular Weight:
~14 kDa observed
Epitope:
UPAR/Ly6 domain
Immunogen:
KLH-conjugated linear peptide corresponding to mouse SCA-1 at the UPAR/Ly6 domain.
Background Information:
Stem cell antigen 1 (SCA-1) is a membrane protein belonging to the Ly-6 family of proteins and contains a single UPAR/Ly6 domain. SCA-1 is involved in the activation of T-cells and is thought to have a critical role in the differentiation, proliferation, and survival of a variety of stem cells. Recent studies have indicated SCA-1 to be an ideal marker for the isolation and purification of stem cells for research and further characterization. It is expressed by both progenitor and stem cells from several tissue types including; cardiac, hematopoietic, mammary, muscle, skin and testis.
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Species Reactivity:
Mouse
Rat
Species Reactivity Note:
Demonstrated to react with mouse and rat.
No Homology to human was found.
Application Notes:
Immunocytochemistry Analysis: A 1:500 dilution from a previous lot detected SCA-1 in rat mesenchymal stem cells.
Control:
Mouse lung tissue lysate
Quality Assurance:
Evaluated by Western Blot in mouse lung tissue lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected SCA-1 in 10 µg of mouse lung tissue lysate.
Purification Method:
Affinity Purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P05533
Entrez Gene Number:
NP_034868
Gene Symbol:
SCA-1
TAP
Alternate Names:
Lymphocyte antigen 6A-2/6E-1
Ly-6A.2/Ly-6E.1
T-cell-activating protein
Stem cell antigen 1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunocytochemistry
UniProt Summary:
FUNCTION: T-cell activation.
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor › GPI-anchor.
TISSUE SPECIFICTY: Widely expressed.
PTM: O-glycosylated. Not N-glycosylated.
Not phosphorylated.
SEQUENCE SIMILARITIES: Contains 1 UPAR/Ly6 domain.
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Product Name:
Anti-SCA-1
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Anti-SCA-1 Antibody is an antibody against SCA-1 for use in WB & IC.

2-8℃