36800   iFluor 750 RGD Conjugate   品牌 AAT

iFluor 750 RGD Conjugate

货号: 36800      产品名称: iFluor 750 RGD Conjugate   品牌: AAT 规格: 1 mg 二周到货 生化试验

iFluor 750 RGD Conjugate
Cat # 36800
Storage F/D/L (see storage codes below)
Unit Size 1 mg
Ex (nm) 750
Em (nm) 780
MW ~1600
Solvent DMSO
Near-infrared fluorescence optical imaging (also called in vivo Imaging) is emerging as a powerful technology for studying diseases at molecular level in small animal models. Water and biological tissues have minimal absorbance and autofluorescence in the NIR window (650_900 nm), thus allowing efficient photon penetration into, and out of tissue with low intra-tissue scattering. Across this NIR window, light absorption by physiologically abundant molecules such as hemoglobin, oxyhemoglobin and deoxyhemoglobin is also reduced to a minimum. In vivo imaging systems with biocompatible fluorescence agents are being developed and optimized for use in the near infrared spectral region – ensuring maximum light penetration and highest sensitivity. The cell adhesion molecule integrin is involved in angiogenesis and metastasis in many tumor types. Integrin is significantly up-regulated in activated endothelial cells and fast-growing solid tumor cells, compared to its minimum expression in quiescent blood vessels and most normal tissues. iFluor� 750-labeled monomeric arginine-glycine-aspartic acid (RGD) peptide c(RGDyK) specifically targets integrin both in cell culture and in living subjects. The in vivo efficacy of iFluor� 750-c(RGDyK) depends on many factors, including the receptor affinity, specificity, molecular size, overall molecular charge, hydrophilicity and metabolic stability. 
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Receptor Binding Assays     Cell Functional Analysis 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)
 

BML-P700-0005   RGD Peptide|正品进口   品牌 Biomol

RGD Peptide|正品进口

货号: BML-P700-0005      产品名称: RGD Peptide|正品进口   品牌: Biomol 规格: 5 mg 3周到货 细胞凋亡

产品参数:
Sequence: Gly-Arg-Gly-Asp-Asn-Pro
MW: 614.6
Purity: ≥97% (HPLC)
Appearance: Lyophilized solid.
Solubility: Soluble in water (>50mg/ml).
Long Term Storage: -20°C
产品说明:
Induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. Does not induce apoptosis in the breast cancer line MCF-7, in which there is a functional deletion of the procaspase-3 gene. Contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. Inhibits cell adhesion of COS-7 cells to fibronectin 80-90% at 1mM.
在各种细胞凋亡和细胞线在1毫米的机制涉及细胞吸收和可能的直接刺激procaspase-3自动处理。并不引起细胞凋亡在乳腺癌行mcf 7,其中有一个功能缺失的procaspase-3基因。包含主题RGD(arg甘胺酸asp)这是发现在许多整合素配体。抑制细胞粘附的因为7细胞纤连蛋白80 – 90%至1毫米。

-20°C

BML-P701-0005   RGD Control Peptide|原装正品   品牌 Biomol

RGD Control Peptide|原装正品

货号: BML-P701-0005      产品名称: RGD Control Peptide|原装正品   品牌: Biomol 规格: 5 mg 3周到货 非活动控制肽

产品说明:
Sequence: Gly-Arg-Ala-Asp-Ser-Pro
MW: 601.6
Purity: 97%
Appearance: Lyophilized solid.
Solubility: Soluble in Water.
Long Term Storage: -20°C
Inactive control peptide.
非活动控制肽。

-20°C