标签归档：reactive

04-461   anti-C-reactive protein(C-term) rb mono   品牌 Millipore

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anti-C-reactive protein(C-term) rb mono

货号： 04-461      产品名称： anti-C-reactive protein(C-term) rb mono   品牌： Millipore 规格： EA 3周到货 生化实验

Anti-c-Reactive Protein (CT) Antibody, rabbit monoclonal
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REFERENCES
Interaction of C-reactive protein with lymphocytes and monocytes: complement-dependent adherence and phagocytosis
Mortensen, R F, et al (1976) J Immunol, 117:774-81 (1976)
Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation
Kleemann, Robert, et al (2003) Blood, 101:545-51 (2003)
Species Reactivity Key Applications Host Format Antibody Type
H  WB, IH(P) Rabbit Purified Monoclonal Antibody
Description:
Anti-c-Reactive Protein (CT) Antibody, rabbit monoclonal
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Trade Name:
Upstate (Millipore)
Specificity:
Recognizes a region composed of residues encompassing the C-terminus of human c-Reactive Protein.
Molecular Weight:
23 kDa
Immunogen:
KLH-conjugated synthetic peptide composed of residues encompassing the C-terminus of human c-Reactive Protein.
Isotype:
IgG
Species Reactivity:
Human
Quality Assurance:
Routinely evaluated by immunoblot.
Presentation:
100 μL of rabbit monoclonal IgG in 60% storage buffer (50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol.
Storage Conditions:
2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.
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UniProt Number:
P02741
Entrez Gene Number:
NM_000567.2
Gene Symbol:
CRP
MGC149895
MGC88244
PTX1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunohistochemistry (Paraffin)
UniProt Summary:
FUNCTION: SwissProt: P02741 # Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
COFACTOR: Binds 2 calcium ions per subunit.
SIZE: 224 amino acids; 25039 Da
SUBUNIT: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Found in plasma.
SIMILARITY: SwissProt: P02741 ## Belongs to the pentaxin family. & Contains 1 pentaxin domain.
MISCELLANEOUS: This protein owes its name to its ability precipitate pneumococcal C-polysaccharide in the presence of calcium.
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Brand Family:
Upstate
Product Name:
Anti-c-Reactive Protein (CT) Antibody, rabbit monoclonal
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 µL
Format:
Purified
Host:
Rabbit
Applications:
Detect c-Reactive Protein (C-term) using this Anti-c-Reactive Protein (C-term) Antibody, Rabbit -20°C

10011236-96   C-Reactive Protein (human) EIA Kit   品牌 Cayman

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C-Reactive Protein (human) EIA Kit

货号： 10011236-96      产品名称： C-Reactive Protein (human) EIA Kit   品牌： Cayman 规格： 96 wells 3周

C-Reactive Protein (human) EIA Kit
Cayman Chemical Item Number 10011236
Description
Limit of detection:46.9 pg/ml · C-Reactive Protein (CRP) is a 224 amino acid protein that is synthesized primarily by hepatocytes, and to a lesser extent adipocytes. CRP plasma levels increase ~1,000-fold in response to acute and chronic inflammatory conditions, making it a useful gauge of inflammation in a wide range of physiological and pathological conditions.1↗ Normal levels of serum CRP (0.64 µg/ml) do not differ between healthy adult men and women, but tend to increase slightly with age.2↗ High plasma CRP concentrations (>3 µg/ml) are associated with an increased risk for atherosclerosis.3↗ CRP has been implicated as a contributor to atherogenesis by modulating endothelial function, stimulating coagulation, inducing the expression of ICAM-1, VCAM-1, and E-selectin, mediating uptake of LDL into macrophages, and destabilizing plaques.1↗,4↗,5↗,6↗,7↗,8↗,9↗ In addition, CRP can bind in a calcium-dependent manner to phosphocholine on microbes, act as a ligand for specific receptors on phagocytic leukocytes, mediate activation of monocytes and macrophages via IL-6, TNF-α and other cytokines, and assist in the complement pathway.1↗,10↗,11↗,12↗ Cayman’s CRP (human) EIA Kit is an immunometric assay which can be used to measure CRP in plasma without prior sample purification. The standard curve spans the range of 0-3,000 pg/ml with a limit of detection of approximately 50 pg/ml.
Synonyms CRP (human) ELISA Kit
Stability 6 months
Storage 4°C
Shipping Wet ice in continental US; may vary elsewhere

4°C

C4063   C Reactive Protein from human plasma   品牌 Sigma

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C Reactive Protein from human plasma

货号： C4063      产品名称： C Reactive Protein from human plasma   品牌： Sigma 规格： 1MG

货号 C4063 | CAS号 9007-41-4 | Sigma
C Reactive Protein 来源于人类血浆
C Reactive Protein from human plasma
buffered aqueous solution
Appearance (Color)             Colorless to Faint Yellow
Appearance (Form)              Solution
Appearance (Turbidity)         Clear to Hazy
mg protein/ml (Lowry w/TCA)    > 0.5 _
Identity                       Human Origin
By OIMM
Purity by SDS Electrophoresis  > 90 % _
Tested For Infectious Agents   Tested