标签： pannexin

ALX-210-949-C100   Pannexin-1 (human), pAb (AT124)   品牌 Alexis

Pannexin-1 (human), pAb (AT124)

货号： ALX-210-949-C100      产品名称： Pannexin-1 (human), pAb (AT124)   品牌： Alexis 规格： 100.micro.g 三周 生化实验

Pannexin-1 (human), pAb (AT124)
Product Specification
Host: Rabbit
Immunogen: Synthetic peptide corresponding to 15 aa near the C-terminus of human pannexin-1.
UniProt ID: Q96RD7
Application: Western Blot (1:1’000)
Specificity: Recognizes human pannexin-1.
Purity Detail: Epitope-affinity purified.
Formulation: Liquid. In PBS containing 0.02% sodium azide.
Use/Stability: Stable for at least 1 year after receipt when stored at -20°C.
Handling: Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C.
Short Term Storage: +4°C
Long Term Storage: -20°C

-20°C

MABN623   Anti-Pannexin-2, clone N121A/3a   品牌 Millipore

Anti-Pannexin-2, clone N121A/3a

货号： MABN623      产品名称： Anti-Pannexin-2, clone N121A/3a   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Pannexin-2, clone N121A/3a
Species Reactivity Key Applications Host Format Antibody Type
R  WB, IHC Mouse Purified Monoclonal Antibody
Description:
Anti-Pannexin-2 Antibody, clone N121A/3a
Specificity:
This antibody does not cross-react with Pannexin 1 and 3 (Prof. J. Trimmer, University of California, Davis.).
Molecular Weight:
~70 kDa observed
Immunogen:
Recombinant protein corresponding to rat Pannexin-2.
Clone:
N121A/31
Isotype:
IgG1κ
Background Information:
The pannexins (Panx), mammalian homologs of invertebrate innexins, belong to the superfamily of gap junction proteins.. Three isoforms of pannexins, Panx1, 2, and 3, have been reported that exhibit high similarity in their amino acid sequence. Panx1 is ubiquitously expressed, however, Panx2 expression is restricted to the central nervous system, and Panx3 is predominantly found in skin, osteoblasts, and specialized cartilage. Panx2 is differentially expressed in multi-potent neuronal progenitor cells and in mature neurons. Panx2 could be present in either S-palmitoylated or non-palmitoylated form. Type I and IIa stem-like neuronal progenitor cells are shown to express an S-palmitoylated version of Panx2 that localizes to Golgi and endoplasmic reticulum membranes. The non-palmitoylated form is expressed mainly in adult hippocampus following granule neuron maturation.
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Species Reactivity:
Rat
Species Reactivity Note:
Demonstrated to react with Rat. Other homologies: Mouse (98% sequence homology)
Application Notes:
Immunohistochemistry Analysis: A representative lot detected Pannexin-2 in rat hippocampus tissue. (Prof. J. Trimmer, University of California, Davis.).
Control:
Rat liver tissue lysate
Quality Assurance:
Evaluated by Western Blotting in rat liver tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Pannexin-2 in 10 µg of rat liver tissue lysate.
Purification Method:
Protein G purified
Presentation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P60571
Entrez Gene Number:
NP_955441
Gene Symbol:
Panx2
Px2
Alternate Names:
Pannexin-2
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunohistochemistry
Product Name:
Anti-Pannexin-2, clone N121A/3a
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 μg
Format:
Purified
Host:
Mouse
Applications:
Anti-Pannexin-2 Antibody, clone N121A/3a is a highly specific mouse monoclonal antibody, that targets Pannexin & has been tested in western blotting & IHC.

2-8℃