标签： ly

1619-1   Enzastaurin (LY317615)   品牌 Biovision

Enzastaurin (LY317615)

货号： 1619-1      产品名称： Enzastaurin (LY317615)   品牌： Biovision 规格： 1 mg 3周到货 生化实验

Enzastaurin (LY317615)
Product Overview
Product Name: Enzastaurin (LY317615)
Alternate Name/Synonyms: LY317615, LY-317615, D04014
Description: Enzastaurin (Enz) is a potent and selective inhibitor of PKCβ with antiproliferative activity (IC₅₀= ~6 nM). Enz suppresses VEGF-induced angiogenesis in the rat corneal micropocket assay, decreases microvessel density, and prevents VEGF secretion from human tumor cell xenografts in nude mice. Prolonged courses of Enz increase chemotherapy or radiation tumor growth delay of glioma, breast, and small cell lung cancer xenografts.
Peptide Sequence: N/A
Appearance: Red-Orange Solid
Formulation: N/A
CAS Number: 170364-57-5
Molecular Formula: C₃₂H₂₉N₅O₂
Molecular Weight: 515.61
Purity: ≥99% by HPLC
Solubility:DMSO (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7
InChi: InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)
InChi Key: AXRCEOKUDYDWLF-UHFFFAOYSA-N
PubChem CID: 176167
MDL Number: MFCD11040980
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1619-5   Enzastaurin (LY317615)   品牌 Biovision

Enzastaurin (LY317615)

货号： 1619-5      产品名称： Enzastaurin (LY317615)   品牌： Biovision 规格： 5 mg 3周到货 生化实验

Enzastaurin (LY317615)
Product Overview
Product Name: Enzastaurin (LY317615)
Alternate Name/Synonyms: LY317615, LY-317615, D04014
Description: Enzastaurin (Enz) is a potent and selective inhibitor of PKCβ with antiproliferative activity (IC₅₀= ~6 nM). Enz suppresses VEGF-induced angiogenesis in the rat corneal micropocket assay, decreases microvessel density, and prevents VEGF secretion from human tumor cell xenografts in nude mice. Prolonged courses of Enz increase chemotherapy or radiation tumor growth delay of glioma, breast, and small cell lung cancer xenografts.
Peptide Sequence: N/A
Appearance: Red-Orange Solid
Formulation: N/A
CAS Number: 170364-57-5
Molecular Formula: C₃₂H₂₉N₅O₂
Molecular Weight: 515.61
Purity: ≥99% by HPLC
Solubility:DMSO (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7
InChi: InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)
InChi Key: AXRCEOKUDYDWLF-UHFFFAOYSA-N
PubChem CID: 176167
MDL Number: MFCD11040980
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1667-25   LY 294002   品牌 Biovision

LY 294002

货号： 1667-25      产品名称： LY 294002   品牌： Biovision 规格： 25 mg 3周到货 生化实验

LY 294002
Product Overview
Product Name: LY 294002
Alternate Name/Synonyms: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Description: A specific and cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 1.40 µM).
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 154447-36-6
Molecular Formula: C₁₉H₁₇NO₃
Molecular Weight: 307.34
Purity: ≥98% by HPLC
Solubility:DMSO (20 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
InChi Key: CZQHHVNHHHRRDU-UHFFFAOYSA-N
PubChem CID: 3973
MDL Number: MFCD00270881
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1747-5   EZSolution LY294002   品牌 Biovision

EZSolution LY294002

货号： 1747-5      产品名称： EZSolution LY294002   品牌： Biovision 规格： 5 mg 3周到货 生化实验

EZSolution™ LY294002
A PI3 Kinase inhibitor
Product Overview
Product Name: EZSolution™ LY294002
Alternate Name/Synonyms: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Description: A 10 mM (5 mg/1627 µl) solution of PI -3 Kinase inhibitor LY 294002 (Cat. No.1667-5) in DMSO.
Peptide Sequence: N/A
Appearance: Liquid
Formulation: 10 mM (DMSO)
CAS Number: 154447-36-6
Molecular Formula: C₁₉H₁₇NO₃
Molecular Weight: 307.34
Purity: ≥98% by HPLC
Solubility:N/A
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
InChi Key: CZQHHVNHHHRRDU-UHFFFAOYSA-N
PubChem CID: 3973
MDL Number: MFCD00270881
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

N0163-100 mg   2-(1,8-Naphthyridin-2-ly)phenol   品牌 LKT

2-(1,8-Naphthyridin-2-ly)phenol

货号： N0163-100 mg      产品名称： 2-(1,8-Naphthyridin-2-ly)phenol   品牌： LKT 规格： 100 mg 三周到货 生化试验

2-(1,8-Naphthyridin-2-ly)phenol
Description
It was shown to enhance IFN-g ability to inhibit the proliferation of human breast cancer and fibrosarcoma cells.
Specifications 
Cas No. 65182-56-1
Product ID  N0163
Product Name  2-(1,8-Naphthyridin-2-ly)phenol
Formula Wt. 222.24
Store Temp
References Lynch RA, Etchin J, Battle TE, Frank DA Cancer Res. 67: 1254-1261 (2007).
 

2156-250   LY-333,531 hydrochloride   品牌 Biovision

LY-333,531 hydrochloride

货号： 2156-250      产品名称： LY-333,531 hydrochloride   品牌： Biovision 规格： 250 μg 3周到货 生化实验

LY-333,531 hydrochloride
A protein kinase Cβ inhibitor
Product Overview
Product Name: LY-333,531 hydrochloride
Alternate Name/Synonyms: Ruboxistaurin
Description: An isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Inhibits both the PKCβI (IC₅₀ = 4.7 nM) and PKCβII (IC₅₀ = 5.9 nM) isozymes. LY-333,531 is 76- and 61-fold more selective for inhibition of PKCβI and PKCβII over PKCα.
Peptide Sequence: N/A
Appearance: Red solid
Formulation: N/A
CAS Number: 169939-93-9
Molecular Formula: C₂₈H₂₉ClN₄O₃
Molecular Weight: 505.01
Purity: ≥98% by NMR
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
InChi: InChI=1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H/t18-;/m0./s1
InChi Key: NYQIEYDJYFVLPO-FERBBOLQSA-N
PubChem CID: 9870785
MDL Number: MFCD08702685
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

2156-1000   LY-333,531 hydrochloride   品牌 Biovision

LY-333,531 hydrochloride

货号： 2156-1000      产品名称： LY-333,531 hydrochloride   品牌： Biovision 规格： 1 mg 3周到货 生化实验

LY-333,531 hydrochloride
A protein kinase Cβ inhibitor
Product Overview
Product Name: LY-333,531 hydrochloride
Alternate Name/Synonyms: Ruboxistaurin
Description: An isozyme-selective inhibitor of protein kinase Cβ (PKCβ). Inhibits both the PKCβI (IC₅₀ = 4.7 nM) and PKCβII (IC₅₀ = 5.9 nM) isozymes. LY-333,531 is 76- and 61-fold more selective for inhibition of PKCβI and PKCβII over PKCα.
Peptide Sequence: N/A
Appearance: Red solid
Formulation: N/A
CAS Number: 169939-93-9
Molecular Formula: C₂₈H₂₉ClN₄O₃
Molecular Weight: 505.01
Purity: ≥98% by NMR
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CN(C)CC1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
InChi: InChI=1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H/t18-;/m0./s1
InChi Key: NYQIEYDJYFVLPO-FERBBOLQSA-N
PubChem CID: 9870785
MDL Number: MFCD08702685
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

L-7962-1 g   LY-294002   品牌 LC

LY-294002

货号： L-7962-1 g      产品名称： LY-294002   品牌： LC 规格： 1 g

L-7962 LY 294002, Free Base, >99%M.W. 307.34 C19H17NO3 [154447-36-6] Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO or ethanol. Appearance: Off-white to cream solid. Disposal: A •Specific inhibitor (IC50 = 1.40 µM) of phosphatidylinositol 3-kinase (PI3K). Vlahos, C.J., et al. “A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4- morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).” J. Biol. Chem. 269: 5241-5248 (1994). •Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.

L-7962-100 mg   LY-294002   品牌 LC

LY-294002

货号： L-7962-100 mg      产品名称： LY-294002   品牌： LC 规格： 100 mg

L-7962 LY 294002, Free Base, >99%M.W. 307.34 C19H17NO3 [154447-36-6] Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO or ethanol. Appearance: Off-white to cream solid. Disposal: A •Specific inhibitor (IC50 = 1.40 µM) of phosphatidylinositol 3-kinase (PI3K). Vlahos, C.J., et al. “A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4- morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).” J. Biol. Chem. 269: 5241-5248 (1994). •Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.

L-7962-200 mg   LY-294002   品牌 LC

LY-294002

货号： L-7962-200 mg      产品名称： LY-294002   品牌： LC 规格： 200 mg

L-7962 LY 294002, Free Base, >99%M.W. 307.34 C19H17NO3 [154447-36-6] Storage: Store at or below -20 ºC. Solubility: Soluble in DMSO or ethanol. Appearance: Off-white to cream solid. Disposal: A •Specific inhibitor (IC50 = 1.40 µM) of phosphatidylinositol 3-kinase (PI3K). Vlahos, C.J., et al. “A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4- morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).” J. Biol. Chem. 269: 5241-5248 (1994). •Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.