标签归档：igf

4120-50   IGF-I, murine recombinant   品牌 Biovision

发表于由

IGF-I, murine recombinant

货号： 4120-50      产品名称： IGF-I, murine recombinant   品牌： Biovision 规格： 50 μg 3周到货 生化实验

IGF-I, murine recombinant
An endocrine hormone binding to IGF1R
Product Overview
Product Name: IGF-I, murine recombinant
Alternate Names / Synonyms: Murine IGF-I, IGF-I, IGFI, IGF I, IGF-1, IGF 1, IGF1, IGFI m-IGF-I, rm-IGF-I, recombinant murine IGF-I, recombinant IGF-I, IGF
Gene Symbol: IGF1A
Accession #: P05017
Gene ID: 16000
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 7.6 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by cell proliferation assay using FDC-P1 cells is <2.0 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg. For most in vitro applications, the IGF-I exerts its biological activity in the concentration range of 1 to 20 ng/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: IGF-I (insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. Murine IGF-I is a 7.6 kDa protein containing 70 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

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4122-10   IGF-II, human recombinant   品牌 Biovision

发表于由

IGF-II, human recombinant

货号： 4122-10      产品名称： IGF-II, human recombinant   品牌： Biovision 规格： 10 μg 3周到货 生化实验

IGF-II, human recombinant
A growth promoting hormone during gestation
Product Overview
Alternate Names / Synonyms: Insulin-like Growth Factor-II, Somatamedin A
Gene Symbol: IGF2
Accession #: P01344
Gene ID: 3481
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives.
Molecular Weight: 7.5 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The recombinant human IGF-II is biologically active when compared to standard. The ED₅₀ as determined by competitive binding against plasma-derived IGF-II to human placental membranes is <1.0 ng/ml, corresponding to a specific activity of >1 x 10⁶ units/mg.
Reconstitution Instructions: Reconstitute in 10 mM acetic acid to a concentration of 0.1-1 mg/ml. This solution can be diluted into other aqueous buffers and or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: IGF-II (insulin-like Growth Factor-II) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types. Human IGF-II is a 7.5 kDa protein containing 67 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

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4216-100   IGF-I, Long R3, human recombinant   品牌 Biovision

发表于由

IGF-I, Long R3, human recombinant

货号： 4216-100      产品名称： IGF-I, Long R3, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

R3 IGF-1, human recombinant
Highly potent form of endocrine hormone IGF-1
Product Overview
Alternate Name/Synonyms: Insulin-like Growth Factor-1, Somatamedin C, IGF-IA
Gene Symbol: IGF1
Accession #: P01343
Gene ID: 3479
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 9.11 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.
Reconstitution Instructions: Reconstitute in dH₂O or 10 mM AcOH to 1.0 mg/ml. This solution can then be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: IGF-1 (insulin-like Growth Factor-1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-1 is a N-terminus modified IGF-1 with a R3 chain, which shows higher potency than regular human IGF-1I in bioactivity assay. The recombinant IGF-1 R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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4216-1G   IGF-I, Long R3, human recombinant   品牌 Biovision

发表于由

IGF-I, Long R3, human recombinant

货号： 4216-1G      产品名称： IGF-I, Long R3, human recombinant   品牌： Biovision 规格： 1 g 3周到货 生化实验

R3 IGF-1, human recombinant
Highly potent form of endocrine hormone IGF-1
Product Overview
Alternate Name/Synonyms: Insulin-like Growth Factor-1, Somatamedin C, IGF-IA
Gene Symbol: IGF1
Accession #: P01343
Gene ID: 3479
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 9.11 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.
Reconstitution Instructions: Reconstitute in dH₂O or 10 mM AcOH to 1.0 mg/ml. This solution can then be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: IGF-1 (insulin-like Growth Factor-1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-1 is a N-terminus modified IGF-1 with a R3 chain, which shows higher potency than regular human IGF-1I in bioactivity assay. The recombinant IGF-1 R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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4216-1MG   IGF-I, Long R3, human recombinant   品牌 Biovision

发表于由

IGF-I, Long R3, human recombinant

货号： 4216-1MG      产品名称： IGF-I, Long R3, human recombinant   品牌： Biovision 规格： 1 mg 3周到货 生化实验

R3 IGF-1, human recombinant
Highly potent form of endocrine hormone IGF-1
Product Overview
Alternate Name/Synonyms: Insulin-like Growth Factor-1, Somatamedin C, IGF-IA
Gene Symbol: IGF1
Accession #: P01343
Gene ID: 3479
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 9.11 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.
Reconstitution Instructions: Reconstitute in dH₂O or 10 mM AcOH to 1.0 mg/ml. This solution can then be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: IGF-1 (insulin-like Growth Factor-1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-1 is a N-terminus modified IGF-1 with a R3 chain, which shows higher potency than regular human IGF-1I in bioactivity assay. The recombinant IGF-1 R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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4216-5MG   Long R3 IGF-I, human recombinant   品牌 Biovision

发表于由

Long R3 IGF-I, human recombinant

货号： 4216-5MG      产品名称： Long R3 IGF-I, human recombinant   品牌： Biovision 规格： 5 mg 3周到货 生化实验

R3 IGF-1, human recombinant
Highly potent form of endocrine hormone IGF-1
Product Overview
Alternate Name/Synonyms: Insulin-like Growth Factor-1, Somatamedin C, IGF-IA
Gene Symbol: IGF1
Accession #: P01343
Gene ID: 3479
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 9.11 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.
Reconstitution Instructions: Reconstitute in dH₂O or 10 mM AcOH to 1.0 mg/ml. This solution can then be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: IGF-1 (insulin-like Growth Factor-1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-1 is a N-terminus modified IGF-1 with a R3 chain, which shows higher potency than regular human IGF-1I in bioactivity assay. The recombinant IGF-1 R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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4216-20MG   Long R3 IGF-I, human recombinant   品牌 Biovision

发表于由

Long R3 IGF-I, human recombinant

货号： 4216-20MG      产品名称： Long R3 IGF-I, human recombinant   品牌： Biovision 规格： 20 mg 3周到货 生化实验

R3 IGF-1, human recombinant
Highly potent form of endocrine hormone IGF-1
Product Overview
Alternate Name/Synonyms: Insulin-like Growth Factor-1, Somatamedin C, IGF-IA
Gene Symbol: IGF1
Accession #: P01343
Gene ID: 3479
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 9.11 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.
Reconstitution Instructions: Reconstitute in dH₂O or 10 mM AcOH to 1.0 mg/ml. This solution can then be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: IGF-1 (insulin-like Growth Factor-1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-1 is a N-terminus modified IGF-1 with a R3 chain, which shows higher potency than regular human IGF-1I in bioactivity assay. The recombinant IGF-1 R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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4216-50MG   IGF-I, Long R3, human recombinant   品牌 Biovision

发表于由

IGF-I, Long R3, human recombinant

货号： 4216-50MG      产品名称： IGF-I, Long R3, human recombinant   品牌： Biovision 规格： 50 mg 3周到货 生化实验

R3 IGF-1, human recombinant
Highly potent form of endocrine hormone IGF-1
Product Overview
Alternate Name/Synonyms: Insulin-like Growth Factor-1, Somatamedin C, IGF-IA
Gene Symbol: IGF1
Accession #: P01343
Gene ID: 3479
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized with no additives
Molecular Weight: 9.11 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by a cell proliferation assay using NIH3T3 cells is typically 1-6 ng/ml.
Reconstitution Instructions: Reconstitute in dH₂O or 10 mM AcOH to 1.0 mg/ml. This solution can then be diluted into other buffered solutions or stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel Pack
Background Information: IGF-1 (insulin-like Growth Factor-1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. BioVision’s recombinant human IGF-1 is a N-terminus modified IGF-1 with a R3 chain, which shows higher potency than regular human IGF-1I in bioactivity assay. The recombinant IGF-1 R3 was produced from E. coli using Animal Origin Free (AOF) components and therefore it is suitable for bioproduction also. The product can be provided as lyophilized form or liquid form, stable for at least two years.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

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4717-100   IGF-BP1, human recombinant   品牌 Biovision

发表于由

IGF-BP1, human recombinant

货号： 4717-100      产品名称： IGF-BP1, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

IGF-BP1, human recombinant
A protein which binds and prolongs the half-life of the IGFs
Product Overview
Alternate Names / Synonyms: IGF-BP1, human recombinant
Gene Symbol: IBP1
Accession #: P08833
Gene ID: 3484
Source: Nso cells
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 27.57 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by its ability to inhibit IGF-I induced proliferation of NUC-1 cells is ~100 ng/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 255 amino acid residues with N-terminal his-tag.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

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4717-10   IGF-BP1, human recombinant (new size)   品牌 Biovision

发表于由

IGF-BP1, human recombinant (new size)

货号： 4717-10      产品名称： IGF-BP1, human recombinant (new size)   品牌： Biovision 规格： 10 μg 3周到货 生化实验

IGF-BP1, human recombinant
A protein which binds and prolongs the half-life of the IGFs
Product Overview
Alternate Names / Synonyms: IGF-BP1, human recombinant
Gene Symbol: IBP1
Accession #: P08833
Gene ID: 3484
Source: Nso cells
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 27.57 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by its ability to inhibit IGF-I induced proliferation of NUC-1 cells is ~100 ng/ml.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Human IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, decidual, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, whereas nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a single, glycosylated protein consisting of 255 amino acid residues with N-terminal his-tag.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

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4720-100   IGF-BP3, human recombinant   品牌 Biovision

发表于由

IGF-BP3, human recombinant

货号： 4720-100      产品名称： IGF-BP3, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

IGF-BP3, human recombinant
A protein which binds and prolongs the half-life of the IGFs
Product Overview
Alternate Names / Synonyms: Human IGF-BP3, IGF-BP3, IGFBP3, h-IGF-BP3, rh-IGF-BP3, recombinant human IGF-BP1, recombinant IGF-BP1, IGF
Gene Symbol: IBP3
Accession #: P17936
Gene ID: 3486
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 20 mM HCl
Molecular Weight: 28.8 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is <0.2 mg/ml, in the presence of 15 ng/ml of human IGF-II.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Human IGF-BP3, also known as growth-hormone-dependant binding protein, is a 28.9 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals. In addition to its ability to modulate the activity of IGF-I and IGF-2, IGF-BP3 also exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

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4723-100   IGF-BP5, human recombinant   品牌 Biovision

发表于由

IGF-BP5, human recombinant

货号： 4723-100      产品名称： IGF-BP5, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

IGF-BP5, human recombinant
A protein which binds and prolongs the half-life of the IGFs
Product Overview
Alternate Names / Synonyms: Human IGF-BP5, IGF-BP5, IGFBP5, IGF BP5, h-IGF-BP5, rh-IGF-BP5, recombinant human IGF-BP5, recombinant IGF-BP5, IGF
Gene Symbol: IBP5
Accession #: P24593
Gene ID: 3488
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 10 mM Sodium Citrate solution, pH 3.0.
Molecular Weight: 28. 6 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 is <0.3 mg/ml, in the presence of 15 ng/ml of human IGF-II.
Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Human IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by Vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Studies show that IGF-BP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGF-BP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole body growth inhibition, and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

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