标签归档：hif

400084-10MG   HIF Prolyl Hydroxylase Inhibitor   品牌 Merck

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HIF Prolyl Hydroxylase Inhibitor

货号： 400084-10MG      产品名称： HIF Prolyl Hydroxylase Inhibitor   品牌： Merck 规格： *** 3周到货 生化实验

HIF Prolyl Hydroxylase Inhibitor
Form  Tan solid
Molar mass  377.82
Purity  ≥95% by HPLC
Solubility  DMSO
Chemical formula  C21H16ClN3O
CAS number  385786-48-1
商店和运输信息
Storage  -20°C
Ship  Shipped with Blue Ice or with Dry Ice
Standard Handling

-20°C

400088-25MG   HIF-1a Translation Inhibitor, KC7F   品牌 Merck

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HIF-1a Translation Inhibitor, KC7F

货号： 400088-25MG      产品名称： HIF-1a Translation Inhibitor, KC7F   品牌： Merck 规格： *** 3周到货 生化实验

HIF-1α Translation Inhibitor, KC7F2
Form  Beige to tan solid
Molar mass  570.4
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥95% by HPLC
Solubility  DMSO or EtOH
Chemical formula  C16H16Cl4N2O4S4
CAS number  927822-86-4
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling

-20°C

400091-50MG   HIF-Hydroxylase Inhibitor, DMOG   品牌 Merck

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HIF-Hydroxylase Inhibitor, DMOG

货号： 400091-50MG      产品名称： HIF-Hydroxylase Inhibitor, DMOG   品牌： Merck 规格： *** 3周到货 生化实验

HIF-Hydroxylase Inhibitor, DMOG
Form  White solid
Molar mass  175.1
Hygrocopic  是的
Purity  ≥98% by HPLC
Solubility  DMSO
Chemical formula  C6H9NO5
CAS number  89464-63-1
商店和运输信息
Storage  +2°C to +8°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Regulatory Review

2°C – 8°C

BML-SA287-0250   HIF-1alpha, mAb (H1α67)   品牌 Biomol

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HIF-1alpha, mAb (H1α67)

货号： BML-SA287-0250      产品名称： HIF-1alpha, mAb (H1α67)   品牌： Biomol 规格： 250 ul 3周到货 生化实验

HIF-1α, mAb (H1α67)
Product Specification
Alternative Name:Hypoxia-inducible factor 1α, ARNT-interacting protein
Clone:H1α67
Host:Mouse
Isotype:IgG
Immunogen:Recombinant human hypoxia-inducible factor-1α (HIF-1α) (aa 532-528).
UniProt ID:Q16665
Application:Immunoprecipitation
Western Blot
Specificity:Recognizes human, rat and mouse HIF-1α. Detects a band of ~120kDa by Western blot.
Purity Detail:Purified IgG.
Long Term Storage:-80°C

-80°C

BML-SA289-0100   HIF-1alpha mAb (OZ12)   品牌 Biomol

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HIF-1alpha mAb (OZ12)

货号： BML-SA289-0100      产品名称： HIF-1alpha mAb (OZ12)   品牌： Biomol 规格： 100 ug 3周到货 生化实验

HIF-1α, mAb (OZ12)
Product Specification
Alternative Name:Hypoxia-inducible factor 1α, ARNT-interacting protein
Clone:OZ12
Host:Mouse
Isotype:IgG1
Immunogen:Recombinant human hypoxia-inducible factor-1α (HIF-1α).
UniProt ID:Q16665
Application:EMSA (Electrophoretic Mobility Shift Assay)
Specificity:Recognizes human Hif-1α.
Purity Detail:Purified.
Long Term Storage:-80°C

-80°C

400093-10MG   HIF-PHD Inhibitor II, JNJ-42041935   品牌 Merck

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HIF-PHD Inhibitor II, JNJ-42041935

货号： 400093-10MG      产品名称： HIF-PHD Inhibitor II, JNJ-42041935   品牌： Merck 规格： *** 3周到货 生化实验

HIF-PHD Inhibitor II, JNJ-42041935
Form  White solid
Molar mass  346.7
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥99% by HPLC
Solubility  DMSO
Chemical formula  C12H6ClF3N4O3
商店和运输信息
Storage  +2°C to +8°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling

2°C – 8°C

07-1586   Anti-HIF-1-alpha, hydroxyproline (Pr   品牌 Millipore

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Anti-HIF-1-alpha, hydroxyproline (Pr

货号： 07-1586      产品名称： Anti-HIF-1-alpha, hydroxyproline (Pr   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-HIF-1-alpha, hydroxyproline (Pro564)
Species Reactivity Key Applications Host Format Antibody Type
H  WB, PIA Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-HIF-1-alpha Antibody, hydroxyproline (Pro564)
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Specificity:
This antibody recognizes the C-terminal VHL recognition site of HIF-1-alpha hydroxylated at Pro564.
Molecular Weight:
~92 kDa observed
Epitope:
C-terminal VHL recognition site
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal VHL recognition site of human HIF-1-alpha, hydroxyproline (Pro564).
Modifications:
Hydroxylation
Background Information:
Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, HIF-1β (also designated Arnt 1), EPAS-1 (also designated HIF-2α) and HIF-3α, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1α is upregulated and forms a heterodimer with HIF-1β to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription. Hypoxia-inducible expression of some genes such as Glut-1, p53, p21 or Bcl-2, is HIF-1α dependent, whereas expression of others, such as p27, GADD 153 or HO-1, is HIF-1α independent. EPAS-1 and HIF-3α have also been shown to form heterodimeric complexes with Arnt 1 in response to hypoxia.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human.
Application Notes:
Peptide Inhibition Analysis: A representative lot of this antibody was used for peptide blocking using an in vitro transcribed and translated HIF-1-alpha protein.
Control:
In vitro transcribed and translated HIF-1-alpha protein untreated and treated with FeCl2
Quality Assurance:
Evaluated by Western Blot using in vitro transcribed and translated HIF-1-alpha protein untreated and treated with FeCl2.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected in vitro transcribed and translated HIF-1-alpha protein treated with FeCl2.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q16665
Entrez Gene Number:
NP_001521
Gene Symbol:
HIF1A
BHLHE78
MOP1
PASD8
Alternate Names:
Hypoxia-inducible factor 1-alpha
HIF-1-alpha
HIF1-alpha
ARNT-interacting protein
Basic-helix-loop-helix-PAS protein
MOP1
Class E basic helix-loop-helix protein 78
bHLHe78
Member of PAS protein 1
PAS domain-containing protein 8
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Peptide Inhibition Assay
Entrez Gene Summary:
This gene encodes the alpha subunit of transcription factor hypox 2-8℃