HCN1, pAb

货号： BML-SA597-0050      产品名称： HCN1, pAb   品牌： Biomol 规格： 50 ul

HCN1, pAb

货号： BML-SA597-0200      产品名称： HCN1, pAb   品牌： Biomol 规格： 200 ul 3周到货 生化实验

HCN1, pAb
Product Specification
Alternative Name:Hyperpolarization-activated cyclic nucleotide-gated potassium channel 1, HAC2, BCNG1
Host:Rabbit
Immunogen:Synthetic peptide corresponding to aa 6-24 of rat HCN1.
Application:Immunohistochemistry
Western Blot
Specificity:Recognizes human, mouse and rat HCN1.
Formulation:Lyophilized.
Long Term Storage:-80°C

-80°C

HCN2, pAb

货号： BML-SA598-0050      产品名称： HCN2, pAb   品牌： Biomol 规格： 50 ul

HCN2, pAb

货号： BML-SA598-0200      产品名称： HCN2, pAb   品牌： Biomol 规格： 200 ul

HCN4, pAb

货号： BML-SA600-0050      产品名称： HCN4, pAb   品牌： Biomol 规格： 50 ul 3周到货 生化实验

HCN4, pAb
Hyperpolarization-activated cation currents (Ih) appear in the heart and the brain and play a crucial role in controlling electrical pacemaker activity, contributing to biological processes such as heartbeat, sleep-wake cycle and synaptic plasticity. The Ih currents are generated by the Hyperpolarization-activated Cyclic Nucleotide-gated channel family (HCN), which comprises four homologous members, HCN1-4. Each HCN subunit consists of six transmembrane (TM) domains, a pore region between TM5-TM6 and a cyclic nucleotide binding domain in the cytoplasmic C-terminus. The HCN subunits can form functional homomers and can also co-assemble into functional heteromers. The channels are closely related to each other and are about 60% homologous. However, they differ from each other in their cytoplasmic N- and the C-termini. HCN1-4 differ in their speed of activation and the extent to which they are modulated by cAMP. HCN1 is the fastest channel, followed by HCN2, HCN3 and HCN4. This family of channels has been implicated in an alternative mechanism for chronic pain.
Product Specification
Alternative Name:Hyperpolarization-activated cyclic nucleotide-gated potassium channel 4
Host:Rabbit
Immunogen:Recombinant human HCN4 (aa 119-155)
UniProt ID:Q9Y3Q4
Application:Immunohistochemistry
Western Blot
Specificity:Recognizes mouse and rat HCN4.
Formulation:Lyophilized from PBS, pH 7.4, 1% BSA and 0.05% sodium azide.
Long Term Storage:-80°C

-80°C

HCN4, pAb

货号： BML-SA600-0200      产品名称： HCN4, pAb   品牌： Biomol 规格： 200 ul