Brain-Derived Neurotrophic Factor (human) (recombinant)

货号： BML-SE546-0001      产品名称： Brain-Derived Neurotrophic Factor (human) (recombinant)   品牌： Biomol 规格： 1 ug 3周到货 生化实验

Brain derived neurotrophic factor (human), (recombinant)
Trk ligand
Product Specification
Alternative Name:BDNF
Source:Produced in E. coli.
UniProt ID:P23560
Purity:>97%
Application:Growth and differentiation factor for neuronal cultures, receptor binding studies.
Miscellaneous/General:Brain derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic growth factors and is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is also required for differentiation of cortical and hippocampal GABAergic interneurons and induces differentiation of dopaminergic neurons and survival of some neuronal cultures. BDNF is expressed as a larger pro form and is cleaved by proteases into its mature form: a 27 kDa dimer formed by two identical subunits.

Brain-Derived Neurotrophic Factor (human) (recombinant)

货号： BML-SE546-0005      产品名称： Brain-Derived Neurotrophic Factor (human) (recombinant)   品牌： Biomol 规格： 5 ug 3周到货 生化实验

Brain derived neurotrophic factor (human), (recombinant)
Trk ligand
Product Specification
Alternative Name:BDNF
Source:Produced in E. coli.
UniProt ID:P23560
Purity:>97%
Application:Growth and differentiation factor for neuronal cultures, receptor binding studies.
Miscellaneous/General:Brain derived neurotrophic factor (BDNF) is a member of the NGF family of neurotrophic growth factors and is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is also required for differentiation of cortical and hippocampal GABAergic interneurons and induces differentiation of dopaminergic neurons and survival of some neuronal cultures. BDNF is expressed as a larger pro form and is cleaved by proteases into its mature form: a 27 kDa dimer formed by two identical subunits.

Brain-derived Neurotrophic Factor Precursor (human) (recombinant)

货号： BML-SE547-0001      产品名称： Brain-derived Neurotrophic Factor Precursor (human) (recombinant)   品牌： Biomol 规格： 1 ug 3周到货 生化实验

Brain derived neurotrophic factor precursor (mouse), (recombinant)
Trk ligand
Product Specification
Alternative Name:pro-BDNF
Source:Produced in E. coli.
UniProt ID:P21237
Purity:>99%
Application:Growth and differentiation factor for neuronal cultures, receptor binding studies.
Miscellaneous/General:BDNF is a neurotrophic factor expressed by proteolytic cleavage of its precursor, proBDNF. The precursor form was thought to be important for the correct folding, secretion and trafficking of the mature protein. Processes such as neuronal process retraction and neuronal apoptosis were thought to be mediated by the binding of BDNF to p75. The finding that proBDNF, and not mature BDNF, is the preferred ligand for p75 has led to a reexamination of the biological roles of the two forms.

Brain-derived Neurotrophic Factor Precursor (human) (recombinant)

货号： BML-SE547-0005      产品名称： Brain-derived Neurotrophic Factor Precursor (human) (recombinant)   品牌： Biomol 规格： 5 ug 3周到货 生化实验

Brain derived neurotrophic factor precursor (mouse), (recombinant)
Trk ligand
Product Specification
Alternative Name:pro-BDNF
Source:Produced in E. coli.
UniProt ID:P21237
Purity:>99%
Application:Growth and differentiation factor for neuronal cultures, receptor binding studies.
Miscellaneous/General:BDNF is a neurotrophic factor expressed by proteolytic cleavage of its precursor, proBDNF. The precursor form was thought to be important for the correct folding, secretion and trafficking of the mature protein. Processes such as neuronal process retraction and neuronal apoptosis were thought to be mediated by the binding of BDNF to p75. The finding that proBDNF, and not mature BDNF, is the preferred ligand for p75 has led to a reexamination of the biological roles of the two forms.

Brain-derived Neurotrophic Factor Precursor (human) (recombinant) (mutated)

货号： BML-SE548-0001      产品名称： Brain-derived Neurotrophic Factor Precursor (human) (recombinant) (mutated)   品牌： Biomol 规格： 1 ug 3周到货 生化实验

[R112A, R113G]Brain derived neurotrophic factor precursor (mouse), (recombinant)
Trk ligand
Product Specification
Alternative Name:pro-BDNF
Source:Produced in E. coli.
UniProt ID:P21237
Purity:>99%
Application:Growth and differentiation factor for neuronal cultures, receptor binding studies.
Miscellaneous/General:BDNF is a neurotrophic factor expressed by proteolytic cleavage of its precursor, proBDNF. The precursor form was thought to be important for the correct folding, secretion and trafficking of the mature protein. Processes such as neuronal process retraction and neuronal apoptosis were thought to be mediated by the binding of BDNF to p75. The finding that proBDNF, and not mature BDNF, is the preferred ligand for p756 has led to a reexamination of the biological roles of the two forms. The amino acid sequence of proBDNF-mut has been changed to prevent the proteolytic cleavage which results in the formation of mature BDNF.

Brain-derived Neurotrophic Factor Precursor (human) (recombinant) (mutated)

货号： BML-SE548-0005      产品名称： Brain-derived Neurotrophic Factor Precursor (human) (recombinant) (mutated)   品牌： Biomol 规格： 5 ug 3周到货 生化实验

[R112A, R113G]Brain derived neurotrophic factor precursor (mouse), (recombinant)
Trk ligand
Product Specification
Alternative Name:pro-BDNF
Source:Produced in E. coli.
UniProt ID:P21237
Purity:>99%
Application:Growth and differentiation factor for neuronal cultures, receptor binding studies.
Miscellaneous/General:BDNF is a neurotrophic factor expressed by proteolytic cleavage of its precursor, proBDNF. The precursor form was thought to be important for the correct folding, secretion and trafficking of the mature protein. Processes such as neuronal process retraction and neuronal apoptosis were thought to be mediated by the binding of BDNF to p75. The finding that proBDNF, and not mature BDNF, is the preferred ligand for p756 has led to a reexamination of the biological roles of the two forms. The amino acid sequence of proBDNF-mut has been changed to prevent the proteolytic cleavage which results in the formation of mature BDNF.