标签： bmpr

ST1717-100UG   ANTI-BMPR2 MOUSE MAB (4A2)   品牌 Merck

ANTI-BMPR2 MOUSE MAB (4A2)

货号： ST1717-100UG      产品名称： ANTI-BMPR2 MOUSE MAB (4A2)   品牌： Merck 规格： *** 3周到货 生化实验

Anti-BMPR2 Mouse mAb (4A2)
Anti-Bone Morphogenetic Protein Receptor Type 2
Recognizes the BMPR2 protein.
产品信息
Host  Mouse
Isotype  IgG2a
Immunogen  A recombinant polypeptide corresponding to amino acids of 939-1037 human BMPR2, expressed as a GST fusion protein.
Clone  4A2
Form  liquid
Formulation  In PBS, pH 7.2.
Species reactivity  human
Preservative  None
Applications 
Enzyme-Linked Immunosorbent Assay
Avoid freeze/thaw  是的
商店和运输信息
Storage  -20°C
Ship  Blue Ice Only
Regulatory Review

-20°C

10551H08H25   RECOM HU BMPR2 (HIS)   品牌 Invitrogen

RECOM HU BMPR2 (HIS)

货号： 10551H08H25      产品名称： RECOM HU BMPR2 (HIS)   品牌： Invitrogen 规格： 25UG 三周到货 生化试验

BMPR2 Recombinant Human Protein (without catalytic activity domain), His tag
Bone morphogenetic protein receptor type II (BMPR2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.
Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ile 151) of human BMPR2 (NP_001195.2) fused to a polyhistidine tag at the C-terminus.
Activity: This recombinant protein has not been tested.
Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.
Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.
Form: Lyophilized 
Purity: ≥ 85% by SDS-PAGE 
Gene ID: 659 
Species: Human 
Expression: Mammalian
Gene Symbol: BMPR2 
Gene Aliases: BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK 
Product Size: 5 x 5 µg 
Protein Form: Recombinant,
Truncated 
Protein Family: Growth Factors & Receptors 
Endotoxin Level: < 1 EU/µg 
Protein Subtype: Serine⁄Threonine Kinases,
Growth Factor Receptors 
Molecular Weight: 15.6 kDa 
Research Category: Stem Cell Research,
Oncology,
Immunology,
Neurobiology,
Cardiovascular Research 
Protein Tag or Fusion: His Tag 
Validated Application: Assay Standard 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at -20 to -70 °C

10551H08H250   RECOM HU BMPR2 (HIS)   品牌 Invitrogen

RECOM HU BMPR2 (HIS)

货号： 10551H08H250      产品名称： RECOM HU BMPR2 (HIS)   品牌： Invitrogen 规格： 250UG 三周到货 生化试验

BMPR2 Recombinant Human Protein (without catalytic activity domain), His tag
Bone morphogenetic protein receptor type II (BMPR2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.
Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ile 151) of human BMPR2 (NP_001195.2) fused to a polyhistidine tag at the C-terminus.
Activity: This recombinant protein has not been tested.
Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.
Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.
Form: Lyophilized 
Purity: ≥ 85% by SDS-PAGE 
Gene ID: 659
Species: Human 
Expression: Mammalian 
Gene Symbol: BMPR2 
Gene Aliases: BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK 
Product Size: 5 x 50 µg 
Protein Form: Recombinant,
Truncated 
Protein Family: Growth Factors & Receptors 
Endotoxin Level: < 1 EU/µg 
Protein Subtype: Serine⁄Threonine Kinases,
Growth Factor Receptors
Molecular Weight: 15.6 kDa 
Research Category: Stem Cell Research,
Oncology,
Immunology,
Neurobiology,
Cardiovascular Research
Protein Tag or Fusion: His Tag 
Validated Application: Assay Standard 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at -20 to -70 °C

10551H08H5   RECOM HU BMPR2 (HIS)   品牌 Invitrogen

RECOM HU BMPR2 (HIS)

货号： 10551H08H5      产品名称： RECOM HU BMPR2 (HIS)   品牌： Invitrogen 规格： 5 UG 三周到货 生化试验

BMPR2 Recombinant Human Protein (without catalytic activity domain), His tag
Bone morphogenetic protein receptor type II (BMPR2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.
Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ile 151) of human BMPR2 (NP_001195.2) fused to a polyhistidine tag at the C-terminus.
Activity: This recombinant protein has not been tested.
Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.
Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.
Form: Lyophilized 
Purity: ≥ 85% by SDS-PAGE 
Gene ID: 659 
Species: Human 
Expression: Mammalian 
Gene Symbol: BMPR2 
Gene Aliases: BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK
Product Size: 5 µg
Protein Form: Recombinant,
Truncated 
Protein Family: Growth Factors & Receptors 
Endotoxin Level: < 1 EU/µg 
Protein Subtype: Serine⁄Threonine Kinases,
Growth Factor Receptors 
Molecular Weight: 15.6 kDa 
Research Category: Immunology,
Cardiovascular Research,
Oncology,
Neurobiology,
Stem Cell Research 
Protein Tag or Fusion: His Tag 
Validated Application: Assay Standard 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at -20 to -70 °C

10551H08H50   RECOM HU BMPR2 (HIS)   品牌 Invitrogen

RECOM HU BMPR2 (HIS)

货号： 10551H08H50      产品名称： RECOM HU BMPR2 (HIS)   品牌： Invitrogen 规格： 50UG 三周到货 生化试验

BMPR2 Recombinant Human Protein (without catalytic activity domain), His tag
Bone morphogenetic protein receptor type II (BMPR2), recombinant human protein is supplied as a lyophilized powder. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.
Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..
This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Ile 151) of human BMPR2 (NP_001195.2) fused to a polyhistidine tag at the C-terminus.
Activity: This recombinant protein has not been tested.
Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.
Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.
Form: Lyophilized 
Purity: ≥ 85% by SDS-PAGE 
Gene ID: 659 
Species: Human 
Expression: Mammalian 
Gene Symbol: BMPR2 
Gene Aliases: BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK 
Product Size: 50 µg 
Protein Form: Recombinant,
Truncated 
Protein Family: Growth Factors & Receptors
Endotoxin Level: < 1 EU/µg
Protein Subtype: Serine⁄Threonine Kinases,
Growth Factor Receptors 
Molecular Weight: 15.6 kDa 
Research Category: Stem Cell Research,
Oncology,
Immunology,
Neurobiology,
Cardiovascular Research 
Protein Tag or Fusion: His Tag 
Validated Application: Assay Standard 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at -20 to -70 °C

ABD50   Anti-BMPR-1B   品牌 Millipore

Anti-BMPR-1B

货号： ABD50      产品名称： Anti-BMPR-1B   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-BMPR-1B
Species Reactivity Key Applications Host Format Antibody Type
H, M, R, Rhesus Macaque  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-BMPR-1B Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Specificity:
This antibody recognizes BMPR-1B at the cytoplasmic domain.
Molecular Weight:
~48 kDa observed. The calculated molecular weight is 56 kDa; however, BMPR-1B has been shown as a ~45 kDa band in western blots. (Paradis, F., et al. (2009). Reproduction. 138:115–129.)
Epitope:
Cytoplasmic domain
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human BMPR-1B.
Background Information:
BMPR-1B (bone morphogenic protein receptor type 1B) is a serine-threonine kinase receptor expressed in granulosa cells. Increased expression of BMPR-1B has been linked to increased ovulation rates in some mammals. BMPR-1B has recently been associated with astrogliosis after a spinal cord injury. BMPR-1A and BMPR-1B work together to suppress ovarian tumorigenesis.
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Species Reactivity:
Human
Mouse
Rat
Rhesus Macaque
Species Reactivity Note:
Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Rhesus Macaque based on 100% sequence homology.
Application Notes:
Western Blot Analysis: 0.5 – 1 µg/mL from a representative lot detected BMPR-1B on 10 µg of mouse ovary tissue and L6 cell lysates.
Control:
Human ovary tissue lysate
Quality Assurance:
Evaluated by Western Blot in human ovary tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected BMPR-1B on 10 µg of human ovary tissue lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
O00238
Entrez Gene Number:
NP_001194
Gene Symbol:
BMPR1B
Alternate Names:
Bone morphogenetic protein receptor type-1B
BMP type-1B receptor
BMPR-1B
CDw293
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Entrez Gene Summary:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. [provided by RefSeq].
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UniProt Summary:
FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine 2-8℃

ABD51   Anti-BMPR-1A   品牌 Millipore

Anti-BMPR-1A

货号： ABD51      产品名称： Anti-BMPR-1A   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-BMPR-1A
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-BMPR-1A Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Specificity:
This antibody recognizes BMPR-1A at the extracellular domain.
Molecular Weight:
~75 kDa observed. The calculated molecular weight is 67 kDa; however, BMPR-1A has been shown as a ~77 kDa band in western blots (Koenig, B., et al. (1994). Molecular and Cellular Biology. 14(9):5961-5974).
Epitope:
Extracellular domain
Immunogen:
KLH-conjugated linear peptide corresponding to the extracellular domain of human BMPR-1A.
Background Information:
BMPR-1A (bone morphogenic protein receptor type 1A) signaling is known to be important for inner root sheath differentiation, hair follicle cycling and tooth development. Mutations in BMPR-1A are a common cause of juvenile polyposis syndrome (JPS). BMPR-1A is expressed in a high quantity during the formation of the primary and secondary palate and the loss of BMPR-1A could be a cause for the cleft palate birth defect.
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Species Reactivity:
Human
Mouse
Rat
Control:
NIH/3T3 cell lysate
Quality Assurance:
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected BMPR-1A on 10 µg of NIH/3T3 cell lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P36894
Entrez Gene Number:
NP_004320
Gene Symbol:
BMPR1A
ACVRLK3
ALK3
Alternate Names:
Bone morphogenetic protein receptor type-1A
BMP type-1A receptor
BMPR-1A
Activin receptor-like kinase 3
ALK-3
Serine/threonine-protein kinase receptor R5
SKR5
CD_antigen=CD292
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Entrez Gene Summary:
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq].
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UniProt Summary:
FUNCTION: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators 2-8℃