标签归档：asp

V1621   Asp-N, Sequencing Grade   品牌 Promega

发表于由

Asp-N, Sequencing Grade

货号： V1621      产品名称： Asp-N, Sequencing Grade   品牌： Promega 规格： 2μg 二周到货 生化试验

说明 
 Asp-N, Sequencing Grade(Asp-N，测序级) 是一种蛋白内切酶，能水解天冬氨酸残基(Asp) 和半胱氨酸残基(Cys) N 末端的肽键。当 pH 范围在 4.0-9.0 时， Asp-N 的活性最佳。该测序级蛋白酶可以单独使用，也可以与其它蛋白酶一起使用，以产生蛋白消化物，然后通过肽指纹图谱或 MS/MS 光谱匹配用于肽图谱或蛋白鉴定。该测序级蛋白酶适合于溶液或凝胶中的消化反应。

 

 

A5275-5 mg   Angiotensin I [Des-Asp1-], human   品牌 LKT

发表于由

Angiotensin I [Des-Asp1-], human

货号： A5275-5 mg      产品名称： Angiotensin I [Des-Asp1-], human   品牌： LKT 规格： 5 mg 三周到货 生化试验

Angiotensin I [Des-Asp1-], human      
Specifications 
Product ID  A5275
Product Name  Angiotensin I [Des-Asp1-], human
Formula Wt. 1181.42
Store Temp +4oC
 

 

+4oC

10017-500   N-Ac-Asp-Glu-Val-Asp-CHO   品牌 Cayman

发表于由

N-Ac-Asp-Glu-Val-Asp-CHO

货号： 10017-500      产品名称： N-Ac-Asp-Glu-Val-Asp-CHO   品牌： Cayman 规格： 500 碌g 3周

N-Ac-Asp-Glu-Val-Asp-CHO Cayman Chemical Item Number 10017 Description N-Ac-Asp-Glu-Val-Asp-CHO is a potent inhibitor of the Group II caspases, caspase-3 and caspase-7 (Kis = 0.23 and 1.6 nM, respectively).1↗,2↗ Notably, it also inhibits other caspases (Kis = 18, 1710, 132, 205, 31, 0.92, 60, and 12 nM for caspases-1, -2, -4, -5, -6, -8, -9, and -10, respectively).1↗ Caspase inhibitors in the aldehyde form, like this compound, are typically reversible, whereas methyl ketone forms, like Ac-DEVD-CMK (Item No. 14465), are irreversible.1↗ Caspase inhibitors interfere with the initiation of apoptosis and have numerous possible clinical applications.3↗ Synonyms Ac-DEVD-CHO Formal Name N-​acetyl-​L-​α-​aspartyl-​L-​α-​glutamyl-​N-​(2-​carboxyl-​1-​formylethyl)-​L-​valinamide CAS Number 184179-08-6 Molecular Formula C20H30N4O11 Formula Weight 502.5 Formulation A crystalline solid Purity >98% Stability 2 years Storage -20°C Shipping Room temperature in continental US; may vary elsewhere SMILES O=C[C@H]​(CC(=O)​O)​NC(=O)​[C@@H]​(NC(=O)​[C@H]​(CCC(=O)​O)​NC(=O)​[C@H]​(CC(=O)​O)​NC(=O)​C)​C(C)​C InCHI Code ​1S/C20H30N4O11/c1-9(2)​17(20(35)​22-11(8-25)​6-15(29)​30)​24-18(33)​12(4-5-14(27)​28)​23-19(34)​13(7-16(31)​32)​21-10(3)​26/h8-9,11-13,17H,4-7H2,1-3H3,(H,21,26)​(H,22,35)​(H,23,34)​(H,24,33)​(H,27,28)​(H,29,30)​(H,31,32)​/t11,12-,13-,17-/m0/s1 InCHI Key UMBVAPCONCILTL-QCDIVLGDSA-N -20°C

10008673-96   ASP EIA Kit   品牌 Cayman

发表于由

ASP EIA Kit

货号： 10008673-96      产品名称： ASP EIA Kit   品牌： Cayman 规格： 96 wells 3周

ASP EIA Kit
Description
Limit of detection:80% B/B0: 10 pg/ml · Domoic acid (DA) and DA derivatives are water-soluble neurotoxins produced by a number of marine algae, in particular those of the genus Pseudo-nitzschia. Blooms of Pseudo-nitzschia may lead to the accumulation of DA in shellfish filter feeders and other marine species. Ingestion of DA-contaminated shellfish causes amnesic shellfish poisoning (ASP) and has been linked to the death of animal and human consumers in severe cases. The European Commission Directive 2002/226/EC has implemented a maximum permitted level (MPL) of 20 mg DA/kg shellfish flesh intended for human consumption, and this level has been adopted by regulatory authorities in most other countries. The ASP ELISA is specific for DA with no cross-reactivity to non-toxic, structural analogues like kainic acid, L-glutamic acid, L-glutamine, formimino-L-glutamic acid, proline or γ-aminobutyric acid (GABA). The assay is primarily intended for use in routine monitoring of DA levels in bivalve molluscs to comply with the regulatory MPL, but is also applicable for DA quantification in other marine matrices.
Synonyms
Amnesic shellfish poison ELISA Kit
A31300401
ASP ELISA Kit
Stability 3 months
Storage 4°C
Shipping Wet ice in continental US; may vary elsewhere

4°C

ALX-260-029-M010   Z-Asp-2,6-dichlorobenzoyloxymethylketone   品牌 Alexis

发表于由

Z-Asp-2,6-dichlorobenzoyloxymethylketone

货号： ALX-260-029-M010      产品名称： Z-Asp-2,6-dichlorobenzoyloxymethylketone   品牌： Alexis 规格： 10 mg 三周

Z-Asp-2,6-dichlorobenzoyloxymethylketone
Caspase inhibitor
Replaces Prod. #: BML-P415
Irreversible, cell permeable broad-spectrum caspase inhibitor.
Caspase-3 IC50: 1,1µM
Caspase-6 IC50: 4,1µM
Less effective on the inhibition of caspase-1- and 8-like activities.
Inhibits hypoxia-induced apoptosis in neuroblastoma cells.
Product Specification
Alternative Name: Caspase family inhibitor, Z-Asp-CH2-DCB, Z-L-Asp-a-[2,6-(dichlorobenzoyl)oxy]methane
Formula: C20H17Cl2NO7
MW: 454.3
CAS: 153088-73-4
Purity: ≥98% (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in methanol (50mg/ml) or DMSO.
Long Term Storage: -20°C
Use/Stability: Stock solutions should be divided into aliquots and stored at -20°C.
Handling: Keep cool and dry.

-20°C

ALX-260-029-M050   Z-Asp-2,6-dichlorobenzoyloxymethylketone   品牌 Alexis

发表于由

Z-Asp-2,6-dichlorobenzoyloxymethylketone

货号： ALX-260-029-M050      产品名称： Z-Asp-2,6-dichlorobenzoyloxymethylketone   品牌： Alexis 规格： 50 mg 三周 生化实验

Z-Asp-2,6-dichlorobenzoyloxymethylketone
Caspase inhibitor
Replaces Prod. #: BML-P415
Irreversible, cell permeable broad-spectrum caspase inhibitor.
Caspase-3 IC50: 1,1µM
Caspase-6 IC50: 4,1µM
Less effective on the inhibition of caspase-1- and 8-like activities.
Inhibits hypoxia-induced apoptosis in neuroblastoma cells.
Product Specification
Alternative Name: Caspase family inhibitor, Z-Asp-CH2-DCB, Z-L-Asp-a-[2,6-(dichlorobenzoyl)oxy]methane
Formula: C20H17Cl2NO7
MW: 454.3
CAS: 153088-73-4
Purity: ≥98% (TLC)
Appearance: White to off-white powder.
Solubility: Soluble in methanol (50mg/ml) or DMSO.
Long Term Storage: -20°C
Use/Stability: Stock solutions should be divided into aliquots and stored at -20°C.
Handling: Keep cool and dry.

-20°C

T9974-1 mg   [Asp371]Tyrosinase (369-377), human   品牌 LKT

发表于由

[Asp371]Tyrosinase (369-377), human

货号： T9974-1 mg      产品名称： [Asp371]Tyrosinase (369-377), human   品牌： LKT 规格： 1 mg 三周到货 生化试验

[Asp371]Tyrosinase (369-377), human     
Specifications 
Cas No. 9002-10-2
Product ID  T9974
Product Name  [Asp371]Tyrosinase (369-377), human
Formula Wt. 1031.2
Purity ≥98% 
Store Temp +4oC
 

+4oC

ALX-350-173-C025   [D-Asp3]-Microcystin-LR   品牌 Alexis

发表于由

[D-Asp3]-Microcystin-LR

货号： ALX-350-173-C025      产品名称： [D-Asp3]-Microcystin-LR   品牌： Alexis 规格： 25.micro.g 3周到货 生化实验

[D-Asp3]microcystin-LR
Isolated from Microcystis aeruginosa. Microcystin containing a leucine (L) in position 2 and arginine (R) in position 4. Additionally, the D-MeAsp at position 3 is demethylated to Asp. Hepatotoxic.
Product Specification
Alternative Name: Microcystin-LR (desmethylated)
Formula: C48H72N10O12
MW: 981.1
Source: Isolated from Microcystis aeruginosa.
Purity: ≥95% (HPLC)
Identity: Identity determined by MS.
Appearance: White to off-white powder or oily film adhered to inside of the vial.
Hazard: HIGHLY IRRITANT.
        MAY BE CARCINOGENIC.
        VERY TOXIC.
Solubility: Soluble in methanol or DMSO.
Long Term Storage: -20°C
Handling: For maximum product recovery after thawing, centrifuge the vial before opening the cap.

-20°C

ALX-350-173-C100   [D-Asp3]-Microcystin-LR   品牌 Alexis

发表于由

[D-Asp3]-Microcystin-LR

货号： ALX-350-173-C100      产品名称： [D-Asp3]-Microcystin-LR   品牌： Alexis 规格： 100.micro.g 3周到货 生化实验

[D-Asp3]microcystin-LR
Isolated from Microcystis aeruginosa. Microcystin containing a leucine (L) in position 2 and arginine (R) in position 4. Additionally, the D-MeAsp at position 3 is demethylated to Asp. Hepatotoxic.
Product Specification
Alternative Name: Microcystin-LR (desmethylated)
Formula: C48H72N10O12
MW: 981.1
Source: Isolated from Microcystis aeruginosa.
Purity: ≥95% (HPLC)
Identity: Identity determined by MS.
Appearance: White to off-white powder or oily film adhered to inside of the vial.
Hazard: HIGHLY IRRITANT.
        MAY BE CARCINOGENIC.
        VERY TOXIC.
Solubility: Soluble in methanol or DMSO.
Long Term Storage: -20°C
Handling: For maximum product recovery after thawing, centrifuge the vial before opening the cap.

-20°C

36-017   A-CLEAVED-TAU (ASP421), CL C3 100UL   品牌 Millipore

发表于由

A-CLEAVED-TAU (ASP421), CL C3 100UL

货号： 36-017      产品名称： A-CLEAVED-TAU (ASP421), CL C3 100UL   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-cleaved-Tau (Asp421) Antibody, clone C3
Close
REFERENCES
Modeling tau polymerization in vitro: a review and synthesis.
Gamblin, T Chris, et al. (2003) Biochemistry, 42: 15009-17 (2003)
The slow axonal transport of the microtubule-associated protein tau and the transport rates of different isoforms and mutants in cultured neurons.
Utton, Michelle A, et al. (2002) J. Neurosci., 22: 6394-400 (2002)
Argyrophilic grain disease is a sporadic 4-repeat tauopathy.
Togo, Takashi, et al. (2002) J. Neuropathol. Exp. Neurol., 61: 547-56 (2002)
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  IP, WB, IHC Mouse Purified Monoclonal Antibody
Description:
Anti-cleaved-Tau (Asp421) Antibody, clone C3
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Specificity:
cleaved-Tau
Molecular Weight:
50-70kDa
Immunogen:
Synthetic peptide corresponding to amino acids 412-421(CSSTGSIDMVD) of human Tau with a Cys at the N-terminal end
Isotype:
IgG1
Species Reactivity:
Human
Mouse
Rat
Quality Assurance:
routinely evaluated by immunoblot on Tau fusion protein cleaved by Caspase 3 (Catalog #14-264)
Purification Method:
Protein A purfied
Presentation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol
Storage Conditions:
2 years at -20°C
UniProt Number:
P10636
Entrez Gene Number:
NM_005910.3
NM_016834.2
NM_016835.2
NM_016841.2
Gene Symbol:
MAPT
MTBT2
MAPTL
PHF-tau
tau
DDPAC
FTDP-17
MGC138549
MSTD
TAU
FLJ31424
MTBT1
PPND
View All »
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Key Applications:
Immunoprecipitation
Western Blotting
Immunohistochemistry
Entrez Gene Summary:
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer’s disease, Pick’s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
View All »
UniProt Summary:
FUNCTION: SwissProt: P10636 # Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
SIZE: 758 amino acids; 78878 Da
SUBUNIT: Interacts with PSMC2 through SQSTM1 (By similarity). Interacts with SQSTM1 when polyubiquitinated.
SUBCELLULAR LOCATION: Cytoplasm, cytosol. Cell membrane. Note=Mostly found in -20℃

5000   FMOC-Asp(EDANS)-OH   品牌 AAT

发表于由

FMOC-Asp(EDANS)-OH

货号： 5000      产品名称： FMOC-Asp(EDANS)-OH   品牌： AAT 规格： 100 mg 二周到货 生化试验

FMOC-Asp(EDANS)-OH
Cat # 5000
Storage F/D/L (see storage codes below)
Unit Size 100 mg
Ex (nm) 335
Em (nm) 493
MW 603.64
Solvent DMF
FMOC-Asp(EDANS)-OH is a building block for in-sequence peptide Asp labeling by EDANS. EDANS is one of the most common donor dyes for preparing FRET peptides (often paired with Dabcyl).
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Dye Labeling Reagents     Fmoc Amino Acids     Carbonyl-Reactive Probes 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

5001   FMOC-Asp(EDANS)-OH   品牌 AAT

发表于由

FMOC-Asp(EDANS)-OH

货号： 5001      产品名称： FMOC-Asp(EDANS)-OH   品牌： AAT 规格： 1 g 二周到货 生化试验

FMOC-Asp(EDANS)-OH
Cat # 5001
Storage F/D/L (see storage codes below)
Unit Size 1 g
Ex (nm) 335
Em (nm) 493
MW 603.64
Solvent DMF
FMOC-Asp(EDANS)-OH is a building block for in-sequence peptide Asp labeling by EDANS. EDANS is one of the most common donor dyes for preparing FRET peptides (often paired with Dabcyl).
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Dye Labeling Reagents     Fmoc Amino Acids     Carbonyl-Reactive Probes 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

5002   FMOC-Asp(EDANS)-OH   品牌 AAT

发表于由

FMOC-Asp(EDANS)-OH

货号： 5002      产品名称： FMOC-Asp(EDANS)-OH   品牌： AAT 规格： 5 g 二周到货 生化试验

FMOC-Asp(EDANS)-OH
Cat # 5002
Storage F/D/L (see storage codes below)
Unit Size 5 g
Ex (nm) 335
Em (nm) 493
MW 603.64
Solvent DMF
FMOC-Asp(EDANS)-OH is a building block for in-sequence peptide Asp labeling by EDANS. EDANS is one of the most common donor dyes for preparing FRET peptides (often paired with Dabcyl).
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Dye Labeling Reagents     Fmoc Amino Acids     Carbonyl-Reactive Probes 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)
 

 

5003   FMOC-Asp(5/6-FAM)-OH   品牌 AAT

发表于由

FMOC-Asp(5/6-FAM)-OH

货号： 5003      产品名称： FMOC-Asp(5/6-FAM)-OH   品牌： AAT 规格： 100 mg 二周到货 生化试验

FMOC-Asp(5/6-FAM)-OH
Cat # 5003
Storage F/D/L (see storage codes below)
Unit Size 100 mg
Ex (nm) 494
Em (nm) 521
MW 755.72
Solvent DMF
FMOC-Asp(5/6-FAM)-OH is a building block for in-sequence peptide Asp labeling by FAM. FAM is one of the most common donor dyes for preparing FRET peptides (often paired with TAMRA or TQ2).
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Dye Labeling Reagents     Fmoc Amino Acids     Carbonyl-Reactive Probes 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

5004   FMOC-Asp(5-FAM)-OH   品牌 AAT

发表于由

FMOC-Asp(5-FAM)-OH

货号： 5004      产品名称： FMOC-Asp(5-FAM)-OH   品牌： AAT 规格： 100 mg 二周到货 生化试验

FMOC-Asp(5-FAM)-OH
Cat # 5004
Storage F/D/L (see storage codes below)
Unit Size 100 mg
Ex (nm) 494
Em (nm) 521
MW 755.72
Solvent DMF
FMOC-Asp(5-FAM)-OH is a building block for in-sequence peptide Asp labeling by FAM. FAM is one of the most common donor dyes for preparing FRET peptides (often paired with TAMRA or TQ2).
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Dye Labeling Reagents     Fmoc Amino Acids     Carbonyl-Reactive Probes 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

5005   FMOC-Asp(5/6-TAMRA)-OH   品牌 AAT

发表于由

FMOC-Asp(5/6-TAMRA)-OH

货号： 5005      产品名称： FMOC-Asp(5/6-TAMRA)-OH   品牌： AAT 规格： 100 mg 二周到货 生化试验

FMOC-Asp(5/6-TAMRA)-OH
Cat # 5005
Storage F/D/L (see storage codes below)
Unit Size 100 mg
Ex (nm) 544
Em (nm) 572
MW 923.89
Solvent DMF
FMOC-Asp(5/6-TAMRA)-OH is a building block for in-sequence peptide Asp labeling by TAMRA. TAMRA is one of the most common donor dyes for preparing FRET peptides (often paired with FAM or TQ3).
Detailed Information:   Protocol      References      MSDS      Spectrum
Related Products:     Dye Labeling Reagents     Fmoc Amino Acids     Carbonyl-Reactive Probes 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)