BML-GR357-0005   Mirin   品牌 Biomol

Mirin

货号: BML-GR357-0005      产品名称: Mirin   品牌: Biomol 规格: 5 mg 3周到货 生化实验

The MRN-ATM pathway is essential for sensing the signaling from DNA double-strand breaks. Mirin is an inhibitor of MRN discovered using a forward chemical genetic screen. It prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity and it inhibits Mre11-associated exonuclease activity. IC50=66μM. It abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Product Specification
Formula:C10H8N2O2S
MW:220.3
CAS:299953-00-7
Purity:95% (TLC)
Appearance:Yellow solid.
Solubility:Soluble in DMSO (25mg/ml) or DMF (25mg/ml).
Long Term Storage:-20°C

-20°C

BML-GR357-0025   Mirin   品牌 Biomol

Mirin

货号: BML-GR357-0025      产品名称: Mirin   品牌: Biomol 规格: 25 mg 3周到货 生化实验

The MRN-ATM pathway is essential for sensing the signaling from DNA double-strand breaks. Mirin is an inhibitor of MRN discovered using a forward chemical genetic screen. It prevents MRN-dependent activation of ATM without affecting ATM protein kinase activity and it inhibits Mre11-associated exonuclease activity. IC50=66μM. It abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Product Specification
Formula:C10H8N2O2S
MW:220.3
CAS:299953-00-7
Purity:95% (TLC)
Appearance:Yellow solid.
Solubility:Soluble in DMSO (25mg/ml) or DMF (25mg/ml).
Long Term Storage:-20°C

-20°C