标签归档：keratin

4817-5   Keratin-8, human recombinant   品牌 Biovision

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Keratin-8, human recombinant

货号： 4817-5      产品名称： Keratin-8, human recombinant   品牌： Biovision 规格： 5 μg 3周到货 生化实验

Keratin-8, human recombinant
Key structural material in skin, hair and nails
Product Overview
Alternate Names / Synonyms: Keratin type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, KRT8, CYK8, KO, CK8, K2C8, CARD2,
Gene Symbol: K8
Accession #: P05787
Gene ID: 3856
Source: E. coli
Appearance: Lyophilized powder
Physical Form Description: Sterile filtered and then lyophilized from 30 mM Tris-HCl, pH 8, 9.5 M urea, 2 mM DTT, 2 mM EDTA and 10 mM methylammonium chloride.
Molecular Weight: 53.5 kDa
Purity by SDS-PAGE: ≥95 %
Purity by HPLC: ≥95 %
Endotoxin Level: <0.1 ng/μg
Biological Activity: N/A
Reconstitution Instructions: Reconstitute in sterile distilled water at a concentration of 100 μg/ml. This can be further diluted into other aqueous solutions.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: Keratin 8 (KRT8) belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin polypeptides 8 and 18. The recombinant human keratin-8 is expressed in E. coli as a single, non-glycosylated polypeptide chain having a molecular mass of 53,532 Dalton and was purified by proprietary chromatographic techniques.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C