ANTI-HNF3B/FOXA2 200UG

货号： 07-633      产品名称： ANTI-HNF3B/FOXA2 200UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-HNF3β/FOXA2 Antibody
Close
REFERENCES
Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells.
K Sekine,T Takebe,Y Suzuki,A Kamiya,H Nakauchi,H Taniguchi (2012) Transplantation proceedings.44
Forkhead Box Protein A2 (FOXA2) Protein Stability and Activity Are Regulated by Sumoylation.
Narasimhaswamy S Belaguli,Mao Zhang,F Charles Brunicardi,David H Berger (2012) PloS one.7
Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells.
Kunisada Y, Tsubooka-Yamazoe N, Shoji M, Hosoya M (2011) Stem cell research
Abnormal notochord branching is associated with foregut malformations in the adriamycin treated mouse model.
Piotr Hajduk,Hideaki Sato,Prem Puri,Paula Murphy (2011) PloS one.6
View All
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  IHC, WB Rabbit Purified Polyclonal Antibody
Description:
Anti-HNF3β/FOXA2 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Specificity:
Recognizes HNF3β/FOXA2.
Molecular Weight:
50 kDa
Immunogen:
GST fusion protein corresponding to residues 7-86 of rat hepatocyte nuclear factor-3 beta / forkhead box A2 (HNF3β/FOXA2)
Isotype:
IgG
Background Information:
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporatic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.
View All »
Species Reactivity:
Human
Mouse
Rat
Control:
MLE 12 nuclear extracts, human liver lysate
Quality Assurance:
Routinely evaluated by immunoblot with nuclear extracts from MLE 12 cells
Purification Method:
Protein A purfied
Presentation:
Protein A Purified rabbit IgG in a solution of 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.135M NaCl, and 0.035% sodium azide as a preservative.
Storage Conditions:
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
UniProt Number:
Q9Y261
Gene Symbol:
FOXA2
MGC19807
HNF-3B
TCF3B
HNF3B
View All »
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Key Applications:
Immunohistochemistry
Western Blotting
Entrez Gene Summary:
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabet -20℃