GDC-0941
货号: 1623-1 产品名称: GDC-0941 品牌: Biovision 规格: 1 mg 3周到货 生化实验
GDC-0941
Product Overview
Product Name: GDC-0941
Alternate Name/Synonyms: 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine
Description: GDC-0941 is a potent inhibitor of p110α and p110δ (IC₅₀ = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 957054-30-7
Molecular Formula: C₂₃H₂₇N₇O₃S₂
Molecular Weight: 513.64
Purity: ≥99% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
InChi: InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
InChi Key: LHNIIDJUOCFXAP-UHFFFAOYSA-N
PubChem CID: 17755052
MDL Number: MFCD11616196
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
1623-5 GDC-0941 品牌 Biovision
GDC-0941
货号: 1623-5 产品名称: GDC-0941 品牌: Biovision 规格: 5 mg 3周到货 生化实验
GDC-0941
Product Overview
Product Name: GDC-0941
Alternate Name/Synonyms: 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine
Description: GDC-0941 is a potent inhibitor of p110α and p110δ (IC₅₀ = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 957054-30-7
Molecular Formula: C₂₃H₂₇N₇O₃S₂
Molecular Weight: 513.64
Purity: ≥99% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
InChi: InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
InChi Key: LHNIIDJUOCFXAP-UHFFFAOYSA-N
PubChem CID: 17755052
MDL Number: MFCD11616196
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
1890-5 GDC-0449 品牌 Biovision
GDC-0449
货号: 1890-5 产品名称: GDC-0449 品牌: Biovision 规格: 5 mg 3周到货 生化实验
GDC-0449
A Smoothened (Smo) antagonist
Product Overview
Product Name: GDC-0449
Alternate Name/Synonyms: 2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
Description: A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 879085-55-9
Molecular Formula: C₁₉H₁₄Cl₂N₂O₃S
Molecular Weight: 421.3
Purity: ≥98% by HPLC
Solubility:DMSO (200 mg/ml) or EtOH (10 mg/ml with warming)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
InChi: InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
InChi Key: BPQMGSKTAYIVFO-UHFFFAOYSA-N
PubChem CID: 24776445
MDL Number: MFCD12407408
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
1890-25 GDC-0449 品牌 Biovision
GDC-0449
货号: 1890-25 产品名称: GDC-0449 品牌: Biovision 规格: 25 mg 3周到货 生化实验
GDC-0449
A Smoothened (Smo) antagonist
Product Overview
Product Name: GDC-0449
Alternate Name/Synonyms: 2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
Description: A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 879085-55-9
Molecular Formula: C₁₉H₁₄Cl₂N₂O₃S
Molecular Weight: 421.3
Purity: ≥98% by HPLC
Solubility:DMSO (200 mg/ml) or EtOH (10 mg/ml with warming)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
InChi: InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
InChi Key: BPQMGSKTAYIVFO-UHFFFAOYSA-N
PubChem CID: 24776445
MDL Number: MFCD12407408
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
11600-10 GDC 0941 品牌 Cayman
GDC 0941
货号: 11600-10 产品名称: GDC 0941 品牌: Cayman 规格: 10 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
11600-100 GDC 0941 品牌 Cayman
GDC 0941
货号: 11600-100 产品名称: GDC 0941 品牌: Cayman 规格: 100 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
11600-50 GDC 0941 品牌 Cayman
GDC 0941
货号: 11600-50 产品名称: GDC 0941 品牌: Cayman 规格: 50 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
13613-10 GDC 0449 品牌 Cayman
GDC 0449
货号: 13613-10 产品名称: GDC 0449 品牌: Cayman 规格: 10 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
13613-25 GDC 0449 品牌 Cayman
GDC 0449
货号: 13613-25 产品名称: GDC 0449 品牌: Cayman 规格: 25 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
13613-5 GDC 0449 品牌 Cayman
GDC 0449
货号: 13613-5 产品名称: GDC 0449 品牌: Cayman 规格: 5 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
13613-50 GDC 0449 品牌 Cayman
GDC 0449
货号: 13613-50 产品名称: GDC 0449 品牌: Cayman 规格: 50 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
G-9252-1 g GDC-0941, Free Base 品牌 LC
GDC-0941, Free Base
货号: G-9252-1 g 产品名称: GDC-0941, Free Base 品牌: LC 规格: 1 g
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
G-9252-100 mg GDC-0941, Free Base 品牌 LC
GDC-0941, Free Base
货号: G-9252-100 mg 产品名称: GDC-0941, Free Base 品牌: LC 规格: 100 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
G-9252-200 mg GDC-0941, Free Base 品牌 LC
GDC-0941, Free Base
货号: G-9252-200 mg 产品名称: GDC-0941, Free Base 品牌: LC 规格: 200 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
G-9252-25 mg GDC-0941, Free Base 品牌 LC
GDC-0941, Free Base
货号: G-9252-25 mg 产品名称: GDC-0941, Free Base 品牌: LC 规格: 25 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
G-9252-50 mg GDC-0941, Free Base 品牌 LC
GDC-0941, Free Base
货号: G-9252-50 mg 产品名称: GDC-0941, Free Base 品牌: LC 规格: 50 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
G-9252-500 mg GDC-0941, Free Base 品牌 LC
GDC-0941, Free Base
货号: G-9252-500 mg 产品名称: GDC-0941, Free Base 品牌: LC 规格: 500 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
17810-1 GDC-0152 品牌 Cayman
GDC-0152
货号: 17810-1 产品名称: GDC-0152 品牌: Cayman 规格: 1 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
17810-10 GDC-0152 品牌 Cayman
GDC-0152
货号: 17810-10 产品名称: GDC-0152 品牌: Cayman 规格: 10 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
17810-5 GDC-0152 品牌 Cayman
GDC-0152
货号: 17810-5 产品名称: GDC-0152 品牌: Cayman 规格: 5 mg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)