tlrl-ednaef   E. coli DNA ef   品牌 Invivogen

E. coli DNA ef

货号: tlrl-ednaef      产品名称: E. coli DNA ef   品牌: Invivogen 规格: 1 mg 二周到货 生化试验

dsDNA-EC
Double-stranded genomic DNA from E. coli K12
dsDNA-EC is an ultrapure, endotoxin-free preparation of E. coli K12 double-stranded DNA.
Intracellular dsDNA-EC can induce type I IFNs in THP1-Blue™ ISG cells, an IRF-SEAP reporter cell line.
Intracellular dsDNA-EC can activate HEK-Blue™ TLR9 cells, NF-κB-SEAP reporter cells that stably overexpress TLR9.
Specificity: CDS agonist and TLR9 agonist
Working Concentration:
• 30 ng – 1 μg/ml transfected dsDNA-EC to activate CDSs
• 10 – 100 μg/ml transfected dsDNA-EC to activate TLR9
Endotoxin level:  < 0.001 EU/µg
Solubility: 1 mg/ml in water

324510-10MG   EF24   品牌 Merck

EF24

货号: 324510-10MG      产品名称: EF24   品牌: Merck 规格: *** 3周到货 生化实验

EF24
3,5-bis-(2-Fluorobenzylidene)-piperidin-4-one, Curcumin Analog, EF24, IKK Inhibitor XIV
A cell-permeable Curcumin (Cat. No. 239802) structural analog that is shown to be at least 10-fold more potent than Curcumin as an IKKβ inhibitor (IC50 = 1.9 µM) and in blocking TNFα-induced cellular I-κB phosphorylation (IC50 = 5.7 µM) and NF-κB nuclear translocation (IC50 = 1.3 µM), as well as in its anticancer activity (IC50 ranges from 0.44 to 2.07 µM) in vitro. Reported to completely stop the expansion of HCT-116-derived tumor in mice (200 µg/kg daily i.p.) in vivo.
产品信息
Form  Yellow solid
Molar mass  311.3
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥97% by HPLC
Solubility  DMSO or EtOH
Chemical formula  C19H15F2NO
商店和运输信息
Storage  +2°C to +8°C
Ship  Ambient Temperature Only
Regulatory Review

2°C – 8°C