Ebselen
货号： 2169-5 产品名称： Ebselen 品牌： Biovision 规格： 5 mg 3周到货 生化实验
Ebselen
A glutathione peroxidase (GPx) mimetic and a peroxynitrite scavenger
Product Overview
Product Name: Ebselen
Alternate Name/Synonyms: 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
Description: An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC₅₀ of 5.17 µM.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 60940-34-3
Molecular Formula: C₁₃H₉NOSe
Molecular Weight: 274.18
Purity: ≥99%
Solubility:DMSO (~ 5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
InChi: InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChi Key: DYEFUKCXAQOFHX-UHFFFAOYSA-N
PubChem CID: 3194
MDL Number: MFCD00210937
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
2169-25 Ebselen 品牌 Biovision
Ebselen
货号： 2169-25 产品名称： Ebselen 品牌： Biovision 规格： 25 mg 3周到货 生化实验
Ebselen
A glutathione peroxidase (GPx) mimetic and a peroxynitrite scavenger
Product Overview
Product Name: Ebselen
Alternate Name/Synonyms: 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one
Description: An organo-selenium compound that displays potent antioxidant properties. Acts as a glutathione peroxidase (GPX) mimic as well as being an excellent scavenger of peroxynitrite. The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase (COX) and lipoxygenases at micromolar concentrations. Also acts as a histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1B protein with an IC₅₀ of 5.17 µM.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 60940-34-3
Molecular Formula: C₁₃H₉NOSe
Molecular Weight: 274.18
Purity: ≥99%
Solubility:DMSO (~ 5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
InChi: InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChi Key: DYEFUKCXAQOFHX-UHFFFAOYSA-N
PubChem CID: 3194
MDL Number: MFCD00210937
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
E0073-25 mg Ebselen 品牌 LKT
Ebselen
货号： E0073-25 mg 产品名称： Ebselen 品牌： LKT 规格： 25 mg 三周到货 生化试验
Ebselen
Description
A seleno-organic compound showing glutathione peroxidase-like activity that has anti-inflammatory, anti-oxidant, and anti-malarial effects. It has been shown to inhibit NO-induced apoptosis of differentiated PC12 cells, and protect Ca2+ blockage.
Specifications
Cas No. 60940-34-3
Product ID E0073
Product Name Ebselen
Synonym 2-Phenyl-1,2-benzisoselenazolin-3-one
Formula Wt. 274.18
Melting Point 180oC-181oC
Purity ≥98%
Solubility Soluble in DMSO.
Store Temp -20oC
References Moretto MB, Franco J, Posser T et al. Neurochem Res. 29:1801-6 (2004). Lindenblatt N, Schareck W, Belusa L et al. Thromb Haemostasis. 90:882-92 (2003). Sarker KP, Biswas KK, Rosales JL et al. J Neurochem. 87:1345-53 (2003).
-20oC
E0073-5 mg Ebselen 品牌 LKT
Ebselen
货号： E0073-5 mg 产品名称： Ebselen 品牌： LKT 规格： 5 mg 三周到货 生化试验
Ebselen
Description
A seleno-organic compound showing glutathione peroxidase-like activity that has anti-inflammatory, anti-oxidant, and anti-malarial effects. It has been shown to inhibit NO-induced apoptosis of differentiated PC12 cells, and protect Ca2+ blockage.
Specifications
Cas No. 60940-34-3
Product ID E0073
Product Name Ebselen
Synonym 2-Phenyl-1,2-benzisoselenazolin-3-one
Formula Wt. 274.18
Melting Point 180oC-181oC
Purity ≥98%
Solubility Soluble in DMSO.
Store Temp -20oC
References Moretto MB, Franco J, Posser T et al. Neurochem Res. 29:1801-6 (2004). Lindenblatt N, Schareck W, Belusa L et al. Thromb Haemostasis. 90:882-92 (2003). Sarker KP, Biswas KK, Rosales JL et al. J Neurochem. 87:1345-53 (2003).
-20oC
10012298-1 Ebselen Oxide 品牌 Cayman
Ebselen Oxide
货号： 10012298-1 产品名称： Ebselen Oxide 品牌： Cayman 规格： 1 mg 3周
Ebselen Oxide
Cayman Chemical Item Number 10012298
Description
Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.1↗
Synonyms NSC 639772
Formal Name 1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
CAS Number 104473-83-8
Molecular Formula C13H9NO2Se
Formula Weight 290.2
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O
InCHI Code 1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
InCHI Key SBTLFLABILGUMK-UHFFFAOYSA-N
-20°C
10012298-10 Ebselen Oxide 品牌 Cayman
Ebselen Oxide
货号： 10012298-10 产品名称： Ebselen Oxide 品牌： Cayman 规格： 10 mg 3周
Ebselen Oxide
Cayman Chemical Item Number 10012298
Description
Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.1↗
Synonyms NSC 639772
Formal Name 1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
CAS Number 104473-83-8
Molecular Formula C13H9NO2Se
Formula Weight 290.2
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O
InCHI Code 1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
InCHI Key SBTLFLABILGUMK-UHFFFAOYSA-N
-20°C
10012298-25 Ebselen Oxide 品牌 Cayman
Ebselen Oxide
货号： 10012298-25 产品名称： Ebselen Oxide 品牌： Cayman 规格： 25 mg 3周
Ebselen Oxide
Cayman Chemical Item Number 10012298
Description
Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.1↗
Synonyms NSC 639772
Formal Name 1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
CAS Number 104473-83-8
Molecular Formula C13H9NO2Se
Formula Weight 290.2
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O
InCHI Code 1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
InCHI Key SBTLFLABILGUMK-UHFFFAOYSA-N
-20°C
10012298-5 Ebselen Oxide 品牌 Cayman
Ebselen Oxide
货号： 10012298-5 产品名称： Ebselen Oxide 品牌： Cayman 规格： 5 mg 3周
Ebselen Oxide
Cayman Chemical Item Number 10012298
Description
Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.1↗
Synonyms NSC 639772
Formal Name 1-oxide-2-phenyl-1,2-benzisoselenazol-3(2H)-one
CAS Number 104473-83-8
Molecular Formula C13H9NO2Se
Formula Weight 290.2
Formulation A crystalline solid
Purity ≥98%
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES O=[Se](N1C2=CC=CC=C2)C3=CC=CC=C3C1=O
InCHI Code 1S/C13H9NO2Se/c15-13-11-8-4-5-9-12(11)17(16)14(13)10-6-2-1-3-7-10/h1-9H
InCHI Key SBTLFLABILGUMK-UHFFFAOYSA-N
-20°C
ALX-270-097-M001 Ebselen 品牌 Alexis
Ebselen
货号： ALX-270-097-M001 产品名称： Ebselen 品牌： Alexis 规格： 1 mg 3周到货 生化实验
Ebselen
Organoselenium compound. Antioxidant.
Replaces Prod. #: BML-EI207
Selenium-based inhibitor of protein kinase C, NADPH, 5-lipoxygenase, cyclooxygenase (COX) and NADPH oxidase. Anti-inflammatory antioxidant. Mimics glutathione peroxidase. Inhibits oxidative modifications of low density lipoproteins (LDL). Protects cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.
Product Specification
Formula: C13H9NOSe
MW: 274.2
CAS: 60940-34-3
Purity: ≥98% (NMR)
Appearance: White to off-white crystalline solid.
Solubility: Soluble in DMSO or 100% ethanol.
Long Term Storage: -20°C
Handling: Protect from light.
-20°C
ALX-270-097-M005 Ebselen 品牌 Alexis
Ebselen
货号： ALX-270-097-M005 产品名称： Ebselen 品牌： Alexis 规格： 5 mg 3周到货 生化实验
Ebselen
Organoselenium compound. Antioxidant.
Replaces Prod. #: BML-EI207
Selenium-based inhibitor of protein kinase C, NADPH, 5-lipoxygenase, cyclooxygenase (COX) and NADPH oxidase. Anti-inflammatory antioxidant. Mimics glutathione peroxidase. Inhibits oxidative modifications of low density lipoproteins (LDL). Protects cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.
Product Specification
Formula: C13H9NOSe
MW: 274.2
CAS: 60940-34-3
Purity: ≥98% (NMR)
Appearance: White to off-white crystalline solid.
Solubility: Soluble in DMSO or 100% ethanol.
Long Term Storage: -20°C
Handling: Protect from light.
-20°C
ALX-270-097-M025 Ebselen 品牌 Alexis
Ebselen
货号： ALX-270-097-M025 产品名称： Ebselen 品牌： Alexis 规格： 25 mg 3周到货 生化实验
Ebselen
Organoselenium compound. Antioxidant.
Replaces Prod. #: BML-EI207
Selenium-based inhibitor of protein kinase C, NADPH, 5-lipoxygenase, cyclooxygenase (COX) and NADPH oxidase. Anti-inflammatory antioxidant. Mimics glutathione peroxidase. Inhibits oxidative modifications of low density lipoproteins (LDL). Protects cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death.
Product Specification
Formula: C13H9NOSe
MW: 274.2
CAS: 60940-34-3
Purity: ≥98% (NMR)
Appearance: White to off-white crystalline solid.
Solubility: Soluble in DMSO or 100% ethanol.
Long Term Storage: -20°C
Handling: Protect from light.
-20°C