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C9754   现货|Colchicine|秋水酰碱|   品牌 Sigma

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现货|Colchicine|秋水酰碱|

货号： C9754      产品名称： 现货|Colchicine|秋水酰碱|   品牌： Sigma 规格： 500mg分 现货

产地：sigma
货号：C9754
秋水仙素
Colchicine
CAS号 64-86-8
分子量 399.44
assay ≥95% (HPLC)
form  powder
color white to yellow with a green cast
mp    150-160 °C (dec.)(lit.)
solubility    H2O: soluble10 mg/mL
Biochem/physiol Actions
Antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

C9754   现货|Colchicine|秋水酰碱|   品牌 Sigma

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现货|Colchicine|秋水酰碱|

货号： C9754      产品名称： 现货|Colchicine|秋水酰碱|   品牌： Sigma 规格： 1g分 现货

产地：sigma
货号：C9754
秋水仙素
Colchicine
CAS号 64-86-8
分子量 399.44
assay ≥95% (HPLC)
form  powder
color white to yellow with a green cast
mp    150-160 °C (dec.)(lit.)
solubility    H2O: soluble10 mg/mL
Biochem/physiol Actions
Antimitotic agent that disrupts microtubules by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

9500C-20   Control siRNA Vector (pGB-control)   品牌 Biovision

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Control siRNA Vector (pGB-control)

货号： 9500C-20      产品名称： Control siRNA Vector (pGB-control)   品牌： Biovision 规格： 20 μg 3周到货 生化实验

Control siRNA Vector (pGB-control)
Product Overview
Product Highlights:
• (GeneBlocker™ siRNA Cloning Vector, pGB)
• Application- The pGB siRNA vectors can be transfected into mammalian cells using Lipofectamine (Invitrogen). For transient transfection, cells can be analyzed in 24-96 hours following transfections, by Western blot analysis or other detection means. For stable transfections, cells can be selected in G418 selection medium to obtain stable cell lines with the specific gene blocked.The pGB cloning vector is designed for cloning your own siRNA insert.
• Features and Positions: Human U6 Promoter: 1-256 Multiple cloning Site: 259-285 3’ Primer: 398-426 (GAAGCATTTATCAGGGTTATTGTCTCATG) SV40 Promoter: 470-808 Neomycin/Kanamycin Resistance ORF: 843-1634 5’ Primer: 2789-2813 (CGTCGATTTTTGTGATGCTCGTCAG) pUC Origin of Replication: 2222-3003
Description: pGB expression vectors contain the human U6 RNA polymerase III promoter, which directs constitutive, high-level expression of short RNA transcripts in many cells. Each vector also contains the neomycin/kanamycin-resistance gene to provide kanamycin resistance in bacteria and the G418 resistance in mammalian cells. The pGB vector is used to clone your own insert. The vector contains two unique restriction sites, BamH I and Xba I for directional cloning. The pGB Negative Control vector contains a insert that does not have significant homology to mammalian genes expressed in human, mouse, and rat, and it can be used as a negative control for pGB-Caspase siRNA vectors. The pGB Caspase siRNA vectors contain the siRNA inserts designed to suppress the expression of each caspase individually
Storage Temp.: -20°C
Shipping: gel pack
Usage: For Research Use Only! Not For Use in Humans.

-20°C

C0143   乙烯利 ETHEPHON   品牌 Sigma

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乙烯利 ETHEPHON

货号： C0143      产品名称： 乙烯利 ETHEPHON   品牌： Sigma 规格： 100MG

中文名称： 乙烯利, 乙烯磷
英文名称： ethrel , ethephon
CAS No.： 16672-87-0
分子式： C2H6CIO3P
分子量： 144.50
溶解性： 易溶于水、甲醇、丙酮、乙二醇、丙二醇，微溶于甲苯，不溶于石油醚。
主要用途： 用作农用植物生长刺激剂。 乙烯利是优质高效植物生长调节剂,具有促进果实成熟,刺激伤流,调节性别转化等效应。
Sigma相关产品资料：
Sigma  C0143  Ethephon
Synonym: 2-Chloroethylphosphonic acid, Ethephon
CAS Number: 16672-87-0
Linear Formula: ClCH2CH2P(O)(OH)2
Molecular Weight: 144.49
Beilstein Registry Number: 1751208
EC Number: 240-718-3
MDL number: MFCD00002142
PubChem Substance ID: 24892237
性质
mp 70-72 °C(lit.)
storage temp. 2-8°C

RT

C7698   正品|Cycloheximide|Naramycin A|放线菌酮|Actidione|环已酰亚胺|   品牌 Sigma

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正品|Cycloheximide|Naramycin A|放线菌酮|Actidione|环已酰亚胺|

货号： C7698      产品名称： 正品|Cycloheximide|Naramycin A|放线菌酮|Actidione|环已酰亚胺|   品牌： Sigma 规格： 1G 大量现货 由产生放线菌酮的放线菌发酵液中提得的一种抗生素

英文名称：actidione, Cycloheximide, Naramycin A
品 名:放线菌酮, 环已酰亚胺
说明:由产生放线菌酮的放线菌发酵液中提得的一种抗生素。无色晶体。熔点119~121℃。易溶于甲醇、乙醇和丙酮，微溶于水。耐酸、耐热。在碱性情况下易分解。对酵母菌、霉菌、原虫等病原菌等有抑制作用。对细菌无显著抑制作用。农业上，用于防治樱桃叶斑病、樱花穿孔病、桃树菌核病、橡树立枯病、薄荷及松树的疱锈病、甘薯黑疤病、菊花黑星病和玫瑰的霉病等。此外，也是鼠类、兔子、狗熊、野猪等的忌避剂。也可由链霉素、制霉菌素等发酵液中的副产物制得。
性状: 无色片状结晶。2℃时溶解度(g/100ml)：水中2.1，乙酸戊酯7.0。溶于氯仿、乙醇、乙醚、丙酮和甲醇。
熔点:119.5-121℃(115-116℃)，比旋光度[α]D25 +6.8˚(c=2，水中)，[α]D29+3.38˚(c=9.47，甲醇中)。有毒，半数致死量(小鼠，静脉)150mg/kg。有刺激性.
Sigma相关产品资料：
Sigma  C7698 Cycloheximide from microbial, ≥94% (TLC)
Synonym: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
CAS Number: 66-81-9

Linear Formula: C15H23NO4
Molecular Weight: 281.35
Beilstein Registry Number: 88868
EC Number: 200-636-0
MDL number: MFCD00082346

PubChem Substance ID: 24892981

Description
Biochem/physiol Actions Cycloheximide (CHX) is an antibiotic produced by S. griseus. Its main biological activity is translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors.
性质
biological source from microbial
assay ≥94% (TLC)
solubility ethanol: soluble, clear to hazy
Gene Information human … FKBP1A(2280), PIN1(5300)

storage temp. 2-8°C

 

 

2-8度

C7698   Cycloheximide|放线菌酮|环已酰亚胺|Actidione|Naramycin A   品牌 Sigma

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Cycloheximide|放线菌酮|环已酰亚胺|Actidione|Naramycin A

货号： C7698      产品名称： Cycloheximide|放线菌酮|环已酰亚胺|Actidione|Naramycin A   品牌： Sigma 规格： 5G 大量现货 凋亡诱导或通过死亡受体促进凋亡诱导

放线菌酮 (CHX) 是由灰色链霉菌产生的抗生素。它的主要生物活性为真核生物中的翻译抑制，从而导致细胞生长停滞和细胞死亡。CHX 广泛用于选择酵母菌和真菌 CHX 耐药株，可控抑制蛋白合成以检测短寿命蛋白和超高诱导蛋白表达，以及进行凋亡诱导或通过死亡受体促进凋亡诱导。
C7698 Sigma
Cycloheximide
from microbial, ≥94% (TLC) DOWNLOAD MSDS (PDF)
Synonym: 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide Actidione Naramycin A
CAS Number 66-81-9
Empirical Formula (Hill Notation) C15H23NO4
Molecular Weight 281.35
biological source    from microbial 
assay    ≥94% (TLC) 
solubility    ethanol: soluble, clear to hazy 
storage temp.    2-8°C 

2-8°C

C2538   正品热销|Carboplatin|卡铂   品牌 Sigma

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正品热销|Carboplatin|卡铂

货号： C2538      产品名称： 正品热销|Carboplatin|卡铂   品牌： Sigma 规格： 50mg 大量现货 抗肿瘤

产品名称：卡铂
英文名称：Carboplatin
分子式： C6H12N2O4Pt
CAS No.：41575-94-4
用途：抗肿瘤
性状：白色结晶粉末
Sigma相关产品资料：
Sigma C2538  Carboplatin
Synonym: cis-Diammine(1,1-cyclobutanedicarboxylato) platinum
CAS Number: 41575-94-4
Linear Formula: [C4H6(CO2)2]Pt(NH3)2
Molecular Weight: 371.25
EC Number: 255-446-0
MDL number: MFCD00070464
PubChem Substance ID: 24278303
Description
Biochem/physiol Actions Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
安全性
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard Codes T
Risk Statements 46-61-20/21/22-42/43
Safety Statements 53-22-26-36/37/39-45
WGK Germany 3
RTECS TP2300000

RT

C4879-500MG   现货|Chymotrypsinogen A|α-Chymotrypsinogen A|胰凝乳蛋白酶原   品牌 Sigma

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现货|Chymotrypsinogen A|α-Chymotrypsinogen A|胰凝乳蛋白酶原

货号： C4879-500MG      产品名称： 现货|Chymotrypsinogen A|α-Chymotrypsinogen A|胰凝乳蛋白酶原   品牌： Sigma 规格： 500MG 大量现货 生化研究,抗溃疡药

产品介绍:
   胰凝乳蛋白酶原 chymotrypsinogen 是胰凝乳蛋白酶的前体物质。牛的胰凝乳蛋白酶原A氨基酸残基245个，分子量24500。
　 白色结晶或粉末。不含盐，由牛胰中提取而得。每mg约含7000单位。可被胰蛋白酶激活，但不被胰凝乳蛋白酶激活。,生化研究。抗溃疡药。
Sigma相关产品资料：
Sigma C4879  α-Chymotrypsinogen A from bovine pancreas
Type II, essentially salt-free, lyophilized powder, ≥40 units/mg solid (after activation to α-chymotrypsin.)
CAS Number:9035-75-0
EC Number:232-905-3
MDL number:MFCD00130483
Description
Biochem/physiol Actions
 A serine protease that hydrolyzes peptide bonds with aromatic or large hydrophobic side chains (Tyr, Trp, Phe, Met) on the carboxyl end of the peptide bond.
Other Notes
View more information on chymotrypsin at Preparation Note
Derived from New Zealand-sourced pancreas.
Unit Definition
One unit will hydrolyze 1.0 μmole of BTEE per min at pH 7.8 at 25 °C.
性质
type:Type II
form:essentially salt-free, lyophilized powder
mol wt:mol wt 25,656 Da by calculation
purified by:6× crystallization
foreign activity:α-chymotrypsin ≤1 unit/mg (prior to activation by trypsin)
storage temp:−20°C

-20度

C0750-25G分   现货|Caffeine|咖啡因|   品牌 Sigma

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现货|Caffeine|咖啡因|

货号： C0750-25G分      产品名称： 现货|Caffeine|咖啡因|   品牌： Sigma 规格： 25G 现货 通过腺苷受体和单胺类神经递质发挥作用的中枢神经系统

C0750-25G分   现货|Caffeine|咖啡因|   品牌 Sigma

咖啡因
Caffeine
CAS号 58-08-2
分子式（希尔表示法） C8H10N4O2
分子量 194.19
一种据信是通过腺苷受体和单胺类神经递质发挥作用的中枢神经系统兴奋剂。它为腺苷受体拮抗剂和腺苷3′，5′-环单磷酸 (cAMP) 磷酸二酯酶抑制剂。因此，在用咖啡因处理后，细胞内 cAMP 的水平将升高。据报道，它会影响细胞的钙水平，从而使细胞内的钙离子外流。它会使多种化学物质(例如蛋白酶抑制剂)的细胞周期效应无效，从而防止细胞凋亡;同时，还发现它可以抑制细胞的 DNA 修复机制。
grade    ReagentPlus
form    powder 
color    white 
mp    234-236.5 °C(lit.) 
solubility    H2O: soluble15 mg/mL
Appearance (Color)             White
Appearance (Form)              Powder
Solubility (Color)             Colorless
Solubility (Turbidity)         Clear
50 mg/mL, CHCl3
Infrared spectrum              Conforms to Structure
Water (by Karl Fischer)        < 0.5 % _
Initial Melting Point          > 233 &deg;C _
Final Melting Point            < 238 &deg;C _
Purity (HPLC)                  > 99.0 % _
Recommended Retest Period      ————————-
4 years

RT

BML-LC004-0050   Leukotriene C4   品牌 Biomol

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Leukotriene C4

货号： BML-LC004-0050      产品名称： Leukotriene C4   品牌： Biomol 规格： 50 ug 3周到货 生化实验

Product Specification
Alternative Name:LTC4, 5S-Hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Formula:C30H47N3O9S
MW:625.8
CAS:72025-60-6
MI:14: 5455
Formulation:Liquid. 50µg/ml in methanol/ammonium acetate buffer, 65:35 pH=5.6.
Purity:≥98% (HPLC)
Long Term Storage:-80°C
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -80°C.

-80°C