Amifostine
货号: BML-GR341-0010 产品名称: Amifostine 品牌: Biomol 规格: 10 mg 3周到货 生化实验
Amifostine is a broad-spectrum radio- and chemoprotector. It restores transcriptional activity of specific p53 mutants, prevents chemotherapy-induced apoptosis and upregulates HIF-1&alpha.
Product Specification
MW:214.2
CAS:20537-88-6
Purity:98%
Long Term Storage:Ambient
Ambient
BML-GR341-0050 Amifostine 品牌 Biomol
Amifostine
货号: BML-GR341-0050 产品名称: Amifostine 品牌: Biomol 规格: 50 mg 3周到货 生化实验
Amifostine is a broad-spectrum radio- and chemoprotector. It restores transcriptional activity of specific p53 mutants, prevents chemotherapy-induced apoptosis and upregulates HIF-1&alpha.
Product Specification
MW:214.2
CAS:20537-88-6
Purity:98%
Long Term Storage:Ambient
Ambient
129874-50MG Amifostine 品牌 Merck
Amifostine
货号: 129874-50MG 产品名称: Amifostine 品牌: Merck 规格: *** 3周到货 生化实验
Amifostine
2-(3-Aminopropyl)aminoethyl phosphorothioate, trihydrate, S-2-(3-Aminopropylamino)ethyl-O,O-dihydrogen phosphorothioate, trihydrate
A cell-permeable aminothiophosphate pro-drug that offers selective protection in many normal, but not in tumor, tissues against the toxic side-effects of radiation and cytotoxic drugs. Its cytoprotective activities have been attributed to its free radical scavenging properties of its active thiol metabolite, WR-1065. The critical step in its activation is its interaction with alkaline phosphatase that is differentially distributed in normal and neoplastic cells. A strong inducer of hypoxia-inducible factor-α1 (HIF-α1) and p53. Shown to reduce PARP proteolysis and levels of active caspase-3 in irradiated mouse ovaries.
产品信息
Form Off-white solid
Molar mass 268.3
Protect from Light 是的
Protect from Moisture 是的
Packaged under inert gas 是的
Purity ≥99% by NMR
Solubility H2O
Chemical formula C5H15N2O3PS •3H2O
CAS number 20537-88-6
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Harmful
安全标示
R Phrase R: 22
Harmful if swallowed.
2°C – 8°C
A4933-100 mg Amifostine 品牌 LKT
Amifostine
货号: A4933-100 mg 产品名称: Amifostine 品牌: LKT 规格: 100 mg 三周到货 生化试验
Amifostine Trihydrate
Description
Amifostine is a chemopreventive drug used to selectively protect normal tissues from the side effects of chemotherapy drugs such as cyclophosphmide, mitomucin-C and cisplatin, and ionising radiation therapy.
Specifications
Cas No. 112901-68-5
Product ID A4933
Product Name Amifostine Trihydrate
Chemical Name Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Synonym Ethiofos; Gammaphos; SAPEP; Ethyol
Formula Wt. 268.27
Purity ≥98%
Solubility Soluble in water.
Store Temp Ambient
References Culy, C.R., Spencer, C.M. Drugs. 61:641-84 (2001). Grdina, D.J., Kataoka, Y., Murley, J.S. Drug Metabol. Drug Interact. 16:237-79 (2000).
室温
A4933-50 mg Amifostine 品牌 LKT
Amifostine
货号: A4933-50 mg 产品名称: Amifostine 品牌: LKT 规格: 50 mg 三周到货 生化试验
Amifostine Trihydrate
Description
Amifostine is a chemopreventive drug used to selectively protect normal tissues from the side effects of chemotherapy drugs such as cyclophosphmide, mitomucin-C and cisplatin, and ionising radiation therapy.
Specifications
Cas No. 112901-68-5
Product ID A4933
Product Name Amifostine Trihydrate
Chemical Name Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Synonym Ethiofos; Gammaphos; SAPEP; Ethyol
Formula Wt. 268.27
Purity ≥98%
Solubility Soluble in water.
Store Temp Ambient
References Culy, C.R., Spencer, C.M. Drugs. 61:641-84 (2001). Grdina, D.J., Kataoka, Y., Murley, J.S. Drug Metabol. Drug Interact. 16:237-79 (2000).
室温
A4933-500 mg Amifostine 品牌 LKT
Amifostine
货号: A4933-500 mg 产品名称: Amifostine 品牌: LKT 规格: 500 mg 三周到货 生化试验
Amifostine Trihydrate
Description
Amifostine is a chemopreventive drug used to selectively protect normal tissues from the side effects of chemotherapy drugs such as cyclophosphmide, mitomucin-C and cisplatin, and ionising radiation therapy.
Specifications
Cas No. 112901-68-5
Product ID A4933
Product Name Amifostine Trihydrate
Chemical Name Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Synonym Ethiofos; Gammaphos; SAPEP; Ethyol
Formula Wt. 268.27
Purity ≥98%
Solubility Soluble in water.
Store Temp Ambient
References Culy, C.R., Spencer, C.M. Drugs. 61:641-84 (2001). Grdina, D.J., Kataoka, Y., Murley, J.S. Drug Metabol. Drug Interact. 16:237-79 (2000).
室温