Optineurin (C-Term) Polyclonal Antibody

货号： 100000-1      产品名称： Optineurin (C-Term) Polyclonal Antibody   品牌： Cayman 规格： EA 3周

Optineurin (C-Term) Polyclonal Antibody
Cayman Chemical Item Number 100000
Description
Antigen:human, mouse, and rat (100% identity) optineurin amino acids 559-575 (GEVLPDIDTLQIHVMDC) · Host:rabbit · Application(s):WB; other applications not tested · Optineurin (originally named FIP-2) is a 74 kDa protein implicated in signal transduction of the tumor necrosis factor (TNF) pathway as well as membrane traffic regulation and cellular morphogenesis. Optineurin protein is also involved in apoptosis, although the exact role is currently unknown. Increased apoptosis of trabecular meshwork cells is a factor in the pathogenesis of glaucoma and mutations in the optineurin gene have been correlated with the some types of the disease. Cayman Chemical is a leading provider of prostaglandin analogs, such as latanoprost and fluprostenol, currently utilized for lowering the intraocular pressure (IOP) associated with glaucoma. Our optineurin polyclonal antibody is another research tool useful for delineating the physiology of the disease.
Synonyms:FIP-2,NRP
Formal Name
Formulation:Peptide affinity-purified IgG
Stability:1 year
Storage:-20°C
Shipping:Room temperature in continental US; may vary elsewhere
Specificity:Human optineurin
Mouse optineurin
Rat optineurin

-20°C