BML-WN115-0005   IQ-1   品牌 Biomol

IQ-1

货号: BML-WN115-0005      产品名称: IQ-1   品牌: Biomol 规格: 5 mg 3周到货 生化实验

IQ-1
Bulk Request
IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription. Upregulates expression of Oct4 and Sox2 transcription factors.
Product Specification
Alternative Name: 2-(4-Acetylphenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide
Formula: C21H22N4O2
MW: 362.4
CAS: 331001-62-8
Purity: ≥98% (TLC)
Appearance: Orange solid.
Solubility: Soluble in DMSO (25mg/ml) or in 100% ethanol (10mg/ml).
Long Term Storage: -20°C
Use/Stability: Stable for at least 6 months after receipt when stored at -20°C. Solutions can be stored at -20°C for up to 3 months.

-20°C

BML-WN115-0025   IQ-1   品牌 Biomol

IQ-1

货号: BML-WN115-0025      产品名称: IQ-1   品牌: Biomol 规格: 25 mg 3周到货 生化实验

IQ-1
Bulk Request
IQ-1 in conjunction with Wnt3a has been shown to be sufficient to maintain murine embryonic stem cell proliferation in the absence of serum. Binds to the PR72/PR130 subunit of protein phosphatase PP2A preventing β-catenin from switching co-activator usage from CBP to p300 leading to an increase in β-catenin/CBP-driven transcription at the expense of β-catenin/p300-driven transcription. Upregulates expression of Oct4 and Sox2 transcription factors.
Product Specification
Alternative Name: 2-(4-Acetylphenylazo)-2-(3,3-dimethyl-3,4-dihydro-2H-isoquinolin-1-ylidene)-acetamide
Formula: C21H22N4O2
MW: 362.4
CAS: 331001-62-8
Purity: ≥98% (TLC)
Appearance: Orange solid.
Solubility: Soluble in DMSO (25mg/ml) or in 100% ethanol (10mg/ml).
Long Term Storage: -20°C
Use/Stability: Stable for at least 6 months after receipt when stored at -20°C. Solutions can be stored at -20°C for up to 3 months.

-20°C

1663-1   IQ-1   品牌 Biovision

IQ-1

货号: 1663-1      产品名称: IQ-1   品牌: Biovision 规格: 1 mg 3周到货 生化实验

IQ-1
Product Overview
Product Name: IQ-1
Alternate Name/Synonyms: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
Description: Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.
Peptide Sequence: N/A
Appearance: Orange solid
Formulation: N/A
CAS Number: 331001-62-8
Molecular Formula: C₂₁H₂₂N₄O₂
Molecular Weight: 362.42
Purity: ≥95% by HPLC
Solubility:DMSO
Storage Temp.: +4°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
InChi: InChI=1S/C21H24N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,18-19,23H,12H2,1-3H3,(H2,22,27)
InChi Key: WQFHCZGUBRVAAW-UHFFFAOYSA-N
PubChem CID: 11152734
MDL Number: MFCD00354369
USAGE: For Research Use Only! Not For Use in Humans.

+4°C