1648-100   Leupeptin, hemisulfate (Microbial)   品牌 Biovision

Leupeptin, hemisulfate (Microbial)

货号: 1648-100      产品名称: Leupeptin, hemisulfate (Microbial)   品牌: Biovision 规格: 100 mg 3周到货 生化实验

Leupeptin, hemisulfate (Synthetic)
Product Overview
Product Name: Leupeptin, hemisulfate (Microbial)
Alternate Name/Synonyms: Ac-Leu-Leu-arginal, hemisulfate, Ac-Leu-Leu-Arginal
Description: A microbial product. A reversible inhibitor of serine and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 103476-89-7
Molecular Formula: C₂₀H₃₈N₆O₄.1/2 H₂SO₄.H₂O
Molecular Weight: 493.61
Purity: ≥90% by HPLC
Solubility: H₂O (10 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C
InChi: InChI=1S/C20H38N6O4/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23)
InChi Key: GDBQQVLCIARPGH-UHFFFAOYSA-N
PubChem CID: 3910
MDL Number: MFCD00037012
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1648-25   Leupeptin, hemisulfate (Microbial)   品牌 Biovision

Leupeptin, hemisulfate (Microbial)

货号: 1648-25      产品名称: Leupeptin, hemisulfate (Microbial)   品牌: Biovision 规格: 25 mg 3周到货 生化实验

Leupeptin, hemisulfate (Synthetic)
Product Overview
Product Name: Leupeptin, hemisulfate (Microbial)
Alternate Name/Synonyms: Ac-Leu-Leu-arginal, hemisulfate, Ac-Leu-Leu-Arginal
Description: A microbial product. A reversible inhibitor of serine and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 103476-89-7
Molecular Formula: C₂₀H₃₈N₆O₄.1/2 H₂SO₄.H₂O
Molecular Weight: 493.61
Purity: ≥90% by HPLC
Solubility: H₂O (10 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C
InChi: InChI=1S/C20H38N6O4/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23)
InChi Key: GDBQQVLCIARPGH-UHFFFAOYSA-N
PubChem CID: 3910
MDL Number: MFCD00037012
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1648-50   Leupeptin, hemisulfate (Microbial)   品牌 Biovision

Leupeptin, hemisulfate (Microbial)

货号: 1648-50      产品名称: Leupeptin, hemisulfate (Microbial)   品牌: Biovision 规格: 50 mg 3周到货 生化实验

Leupeptin, hemisulfate (Synthetic)
Product Overview
Product Name: Leupeptin, hemisulfate (Microbial)
Alternate Name/Synonyms: Ac-Leu-Leu-arginal, hemisulfate, Ac-Leu-Leu-Arginal
Description: A microbial product. A reversible inhibitor of serine and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 103476-89-7
Molecular Formula: C₂₀H₃₈N₆O₄.1/2 H₂SO₄.H₂O
Molecular Weight: 493.61
Purity: ≥90% by HPLC
Solubility: H₂O (10 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C
InChi: InChI=1S/C20H38N6O4/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23)
InChi Key: GDBQQVLCIARPGH-UHFFFAOYSA-N
PubChem CID: 3910
MDL Number: MFCD00037012
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1816-25   Tranylcypromine Hemisulfate   品牌 Biovision

Tranylcypromine Hemisulfate

货号: 1816-25      产品名称: Tranylcypromine Hemisulfate   品牌: Biovision 规格: 25 mg 3周到货 生化实验

Tranylcypromine Hemisulfate
A Lysine-Specific Demethylase 1 (LSD1) inhibitor
Product Overview
Product Name: Tranylcypromine Hemisulfate
Alternate Name/Synonyms: Trans (±)-2-Phenylcyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA
Description: An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC₅₀ <2 µM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021 (Cat. No. 1677-5, 25), causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 13492-01-8
Molecular Formula: C₉H₁₁N.1/2H₂SO₄
Molecular Weight: 182.2
Purity: ≥99% by TLC
Solubility:H₂O (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O
InChi: InChI=1S/C9H11N.H2O4S/c10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h1-5,8-9H,6,10H2;(H2,1,2,3,4)/t8-,9+;/m0./s1
InChi Key: BTHVHSMCHJCPFU-OULXEKPRSA-N
PubChem CID: 6852410
MDL Number: MFCD00079222
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1816-100   Tranylcypromine Hemisulfate   品牌 Biovision

Tranylcypromine Hemisulfate

货号: 1816-100      产品名称: Tranylcypromine Hemisulfate   品牌: Biovision 规格: 100 mg 3周到货 生化实验

Tranylcypromine Hemisulfate
A Lysine-Specific Demethylase 1 (LSD1) inhibitor
Product Overview
Product Name: Tranylcypromine Hemisulfate
Alternate Name/Synonyms: Trans (±)-2-Phenylcyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA
Description: An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC₅₀ <2 µM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021 (Cat. No. 1677-5, 25), causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 13492-01-8
Molecular Formula: C₉H₁₁N.1/2H₂SO₄
Molecular Weight: 182.2
Purity: ≥99% by TLC
Solubility:H₂O (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O
InChi: InChI=1S/C9H11N.H2O4S/c10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h1-5,8-9H,6,10H2;(H2,1,2,3,4)/t8-,9+;/m0./s1
InChi Key: BTHVHSMCHJCPFU-OULXEKPRSA-N
PubChem CID: 6852410
MDL Number: MFCD00079222
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

L2884   现货|Leupeptin hemisulfate salt|亮抑酶肽|Leupeptin   品牌 Sigma

现货|Leupeptin hemisulfate salt|亮抑酶肽|Leupeptin

货号: L2884      产品名称: 现货|Leupeptin hemisulfate salt|亮抑酶肽|Leupeptin   品牌: Sigma 规格: 5MG 大量现货

由玫瑰链霉菌Streptomyces roseus MB-26-AI产生的胰蛋白酶抑剂,它是许多蛋白酶抑制剂中的一种。纯亮肽素熔点110~140℃,旋光度-56°(c=1.0,甲醇)。溶于水、甲醇、乙醇、丁醇、二甲亚砜,不溶于乙酸乙酯、丙酮、氯仿、己烷等,对Rydon-Smith、坂口呈附哇反应,对茚三酮、三氯化铁、蒽酮、莫利氏呈阳性反应。亮肽素可抑制胰蛋白酶、木瓜蛋白酶、组织蛋酶B、血纤维蛋白溶酶、激肽释放酶等,它的抑制作用与底物呈竞争抑制。亮肽素(Leupeptin)能抑制多种丝氨酸和半胱氨酸蛋白酶;抑肽素(pepstatin)抑制天冬氨酸蛋白酶;抑肽酶(aprotinin)能抑制许多丝氨酸蛋白酶;苯丁抑制剂(bestatin)能抑制氨基酸多肽酶 .
别名:亮肽素
分子式:C20H38N6O4 1/2(H2SO4) H20 分子量: 493.62
CAS#:103476-89-7
外观:白色粉末
特性:比旋度(2%, 水):-84.2–82.2
溶解性:溶于水,参考浓度为10mg/ml,工作浓度为 0.5mg/ml。
        储存液4℃保存一周,-20℃保存6个月。
Sigma相关产品信息
Sigma  L2884  Leupeptin hemisulfate salt
microbial, ≥90% (HPLC)
Synonym: Acetyl-Leu-Leu-Arg-al, N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt
CAS Number: 103476-89-7
Linear Formula: C20H38N6O4 • 1/2H2SO4
Molecular Weight: 475.59
MDL number: MFCD00037012
PubChem Substance ID: 24896328
Description
Analysis Note Leupeptin gives multiple peaks on HPLC due to equilibria among three forms in solution. Purity determined using three main peaks. Majority of contaminating peptide is racemized leupeptin.
Biochem/physiol Actions Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain and cathepsin B. No inhibition found with pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. Effective concentration 10-100 μM.
性质
biological source microbial
assay ≥90% (HPLC)
EQP level Premium
solubility H2O: 10 mM (Solutions are stable for a week at 4 °C. Stock solutions are stable up to 6 months at −20 °C.)
storage temp. −20°C

-20度