TNF Receptor-Associated Protein 1 (TRAP1), human recombinant

货号： 7778-10      产品名称： TNF Receptor-Associated Protein 1 (TRAP1), human recombinant   品牌： Biovision 规格： 10 μg 3周到货 生化实验

TNF Receptor-Associated Protein 1 (TRAP1), human recombinant
Interacts with EXT2, EXT1 and Retinoblastoma protein
Product Overview
Alternate Name/Synonyms: Heat shock protein 75 kDa, HSP 75, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP-1
Gene Symbol: TRAP1
Accession #: Q12931
Gene ID: 10131
Source: E. coli.
Appearance: Liquid
Physical Form Description: 50 mM potassium phosphate pH 7.4, 50 mM sodium chloride, 0.5 mM DTT, 0.5 mM EDTA, and 2.5% glycerol.
Molecular Weight: 76.5 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: Kd = 1.95 nM. Assay conditions: 20 mM HEPES, pH 7.5, 50 mM KCl, 5 mM MgCl2, 20 mM sodium molybdate, 2 mM DTT, 0.01% NP40, 100 µg/ml BSA, 50 nM TRAP1, geldanamycin-FITC (titration range 0.016-16 nM) incubated at 4oC for 24 hrs. Fluorescence polarization measured at RT (Ex/Em= 485/520 nm).
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry Ice
Background Information: Human TRAP1 belongs to the mitochondrial heat shock protein family. These molecular chaperones are highly conserved and play an important role in signal transduction, protein folding and degradation. Recombinant human TRAP1 has a C-terminal FLAG tag and has 702 amino acid residues. It has been identified to be protective for cell survival, and has been suggested as a target for anti-cancer therapeutics. Also can be useful for studies including enzyme kinetics, activator screening and selectivity profiling.
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-80°C