Pro-MMP-8, human

货号： 7784-5      产品名称： Pro-MMP-8, human   品牌： Biovision 规格： 5 μg 3周到货 生化实验

Pro-MMP-8, human
A Protein involved in breakdown of extracellular matrix
Product Overview
Alternate Name/Synonyms: MMP-8, matrix metalloproteinase-8, MMP, MMP recombinant, MMP protein
Gene Symbol: MMP8
Accession #: P22894
Gene ID: 4317
Source: Human neutrophil granulocytes (Buffy Coat)
Appearance: Liquid
Physical Form Description: In 50 mM Tris-HCl, pH 7; 200 mM NaCl; 5 mM CaCl₂; 1 μM ZnCl₂; 0.05% Brij 35; 0,05% NaN₃
Molecular Weight: 40/42 kDa
Purity by SDS-PAGE: N/A
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: N/A
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Dry Ice
Background Information: Human neutrophil collagenase (HNC) has been purified from extracts of fresh and outdated buffy coats and from exudates of phorbol myristate acetate-stimulated neutrophils. The MMP-8 present in the starting material can either be latent or active, or have an app. relative molecular mass of 75-kDa and/or 58-kDa. The rather complex pattern of activation of the latent 58-kDa and 75-kDa species by trypsin, organomercurials and oxidants has been investigated. MMP-8 was shown to preferentially hydrolyze type I over type II, and type III collagens in solution and to be a glycoprotein that contains complex N-linked oligosaccharides leading to multiple forms of MMP-8 in SDS-PAGE. The action of endoglycosidase on the latent 58-kDa form produces 42/40-kDa species (Gao et al. 1992, Mallya et al. 1990). This indicates that MMP-8 is an N-linked, complex glycoprotein that appears to be glycosylated at multiple sites
Amino Acid Sequence: N/A
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-80°C