SHIP1 Inhibitor, 3AC

货号： 565835-10MG      产品名称： SHIP1 Inhibitor, 3AC   品牌： Merck 规格： *** 3周到货 生化实验

SHIP1 Inhibitor, 3AC
3α-Aminocholestane, SH2-domain-containing inositol 5′-phosphatase 1 (SHIP1) Inhibitor, 3AC
A cell-permeable steroidal compound that selectively inhibits SHIP1′ polyphosphatase activity toward PI(3,4,5)P3 (IC50 = 10 µM), but not SHIP2 5′ or PTEN′ polyphosphatase activity toward PI(3,4,5)P3 (IC50 > 1 mM). Effectively inhibits SHIP1-mediated immune response both in vitro and in vivo, as well as SHIP1-dependent cancer cell survival. SHIP2 Inhibitor, AS1938909 is also available (Cat. No. 565840).
产品信息
Form  White solid
Molar mass  387.7
Packaged under inert gas  是的
Purity  ≥98% by 1H NMR
Solubility  EtOH
Chemical formula  C27H49N
商店和运输信息
Storage  +2°C to +8°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling

2°C – 8°C