PD 173074
货号： 1675-1 产品名称： PD 173074 品牌： Biovision 规格： 1 mg 3周到货 生化实验
PD 173074
Product Overview
Product Name: PD 173074
Alternate Name/Synonyms: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N’-(1,1-dimethylethyl)urea
Description: A potent and selective FGFR1 tyrosine kinase inhibitor (IC₅₀ = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem cells with PD173074 decreases dramatically their clonogenicity and differentiation potential.
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 219580-11-7
Molecular Formula: C₂₈H₄₁N₇O₃
Molecular Weight: 523.67
Purity: ≥98% by TLC
Solubility:DMSO (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
InChi: InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36)
InChi Key: DXCUKNQANPLTEJ-UHFFFAOYSA-N
PubChem CID: 1401
MDL Number: MFCD11045982
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
