PS48
货号： 1869-25 产品名称： PS48 品牌： Biovision 规格： 25 mg 3周到货 生化实验
PS48
An allosteric PDK1 inhibitor
Product Overview
Product Name: PS48
Alternate Name/Synonyms: (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoic acid
Description: An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently been found that a combination of PS48, sodium butyrate (Cat. No. 1609-1000), a histone deacetylase inhibitor and the gene Oct-4, could enhance the reprogramming efficiency of keratinocytes isolated from human skin or hair follicles over 25-fold.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 1180676-32-7
Molecular Formula: C₁₇H₁₅ClO₂
Molecular Weight: 286.75
Purity: ≥95% by HPLC
Solubility:DMSO (100 mM) or EtOH (50 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC=C(C=C1)C(=CC(=O)O)CCC2=CC=C(C=C2)Cl
InChi: InChI=1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
InChi Key: LLJYFDRQFPQGNY-QINSGFPZSA-N
PubChem CID: 44141940
MDL Number: MFCD17215962
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
