RepSox
货号： 1894-25 产品名称： RepSox 品牌： Biovision 规格： 25 mg 3周到货 生化实验
RepSox
A TGF-β type I receptor (ALK5) inhibitor
Product Overview
Product Name: RepSox
Alternate Name/Synonyms: 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine; E-616452
Description: Cell-permeable. A TGF-β type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC₅₀ = 4 nM). Can replace one of the four reprogramming factors Sox-2. RepSox has been successfully used in the direct reprogramming of mouse fibroblasts through induction of Nanog transcription.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 446859-33-2
Molecular Formula: C₁₇H₁₃N₅
Molecular Weight: 287.32
Purity: ≥98% by HPLC
Solubility:DMSO (>20 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1=CC=CC(=N1)C2=C(C=NN2)C3=NC4=C(C=C3)N=CC=C4
InChi: InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)
InChi Key: LBPKYPYHDKKRFS-UHFFFAOYSA-N
PubChem CID: 449054
MDL Number: MFCD09037561
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
