pUNO1-bTLR5

货号： puno1-btlr5      产品名称： pUNO1-bTLR5   品牌： Invivogen 规格： 1 disk 三周到货 生化试验

TLR5 Native Genes
Toll-Like Receptor 5 native genes in expression plasmid
Alias: CD285
TLR5 is the Toll-like molecule that recognizes flagellin from both Gram-positive and Gram-negative bacteria.
TLR5 was identified by the presence of the TIR domain and is expressed in spleen, peripheral blood leukocytes and epithelial cells.
Activation of the receptor stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88 and the serine kinase IRAK [1, 2]. TLR5 can generate a proinflammatory signal as a homodimer suggesting that it might be the only TLR required for flagellin recognition [2].
This gene is available in pUNO1 expression plasmid selectable with Blasticidin or in pUNO3 expression plasmid selectable with Hygromycin or in pUNO1 expression plasmid selectable with Blasticidin.
Bovine TLR5 (pUNO1-bTLR05)
ORF Size: 2577 bp
Subclone: NcoI – NheI
Human TLR5 (pUNO1-hTLR05)
ORF Size: 2577 bp
Subclone: NcoI – NheI
Human TLR5 (pUNO3-hTLR05)
ORF Size: 2577bp
Subclone: NcoI – NheI
Mouse TLR5 (pUNO1-mTLR05)
ORF Size: 2577 bp
Subclone: NcoI – NheI
Pig TLR5 (pUNO1-pTLR05)
ORF Size: 2571 bp
Subclone: AgeI – NheI