β-Amyloid (1-8, A2V) Peptide Exclusive Cayman Chemical Item Number 10229 Description β-Amyloid peptide (1-42) aggregation results in the formation of neurotoxic fibrils or globular oligomers.1↗ The amyloid precursor protein (APP) mutation Ala673Val results in disease for homozygous carriers but not for heterozygous carriers. The mutation generates β-Amyloid peptide with valine at amino acid position two. Biochemical analysis of Aβ (1-42) aggregation suggests this small peptide may be a useful guide for developing β-amyloid peptide aggregation inhibitors.2↗ Synonyms Aβ 1-8 mutant,β-amyloid (1-8) dominant negative,Aβ Formula Weight 1004.0 Formulation 1 mg lyophilized peptide Stability 1 year Storage -20°C Shipping Room temperature in continental US; may vary elsewhere -20°C
