Doxifluridine-d2
货号： 10010675-10 产品名称： Doxifluridine-d2 品牌： Cayman 规格： 10 mg 3周
Doxifluridine-d2
Cayman Chemical Item Number 10010675
Description Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5′-deoxy-5-fluorocytidine (5′-DFCR) and 5′-deoxy-5-fluorouridine (5′-DFUR), to form 5-flyorouracil.
Synonyms 5-DFUR-d2
Formal Name 5′-deoxy-5-fluoro-uridine-5′,5′-C-d2
CAS Number 84258-25-3
Molecular Formula C9H9D2FN2O4
Formula Weight 248.2
Formulation A crystalline solid
Purity ≥99% deuterated forms (d1-d2)
Stability 1 year
Storage 4°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES O=c1[nH]c(=O)n(cc1F)[C@@H]1O[C@H](C([2H])[2H])C(O)C1O
InCHI Code 1S/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5,6,8-/m1/s1/i1D2
InCHI Key ZWAOHEXOSAUJHY-GUFOIWCCSA-N
4°C
