MEK1 (human) (recombinant) (His-tag)

货号： BML-SE509-0020      产品名称： MEK1 (human) (recombinant) (His-tag)   品牌： Biomol 规格： 20 ug 3周到货 生化实验

MEK1 (human), (recombinant) (His-tag)
Product Specification
Alternative Name:MAPK2K1, MAPKK1, MAP kinase kinase 1, MAPK/ERK kinase 1
MW:~43kDa
Source:Produced in E. coli. Active full length MEK1 (MAPK2K1) with C- and N-terminal His-tags. Genbank ID No. NM_002755.
UniProt ID:Q02750
Formulation:Liquid. In 50mM TRIS-HCl, pH 8.0, containing 150mM sodium chloride, 5mM DTT, 0.03% Brij-35, 20% glycerol.
Purity:≥85% (SDS-PAGE)
Purity Detail:Purified by multi-step chromatography.
Specific Activity:≥12 pmol/min/µg. Kinase activity was measured using the non-radioactive ADP Hunter Plus kit™.
Application:Study enzyme regulation and kinetics, phosphorylate target substrates, screen for inhibitors.
Long Term Storage:-80°C
Use/Stability:After initial defrost, aliquot product into individual tubes and refreeze at -80°C. Avoid repeated freeze/defrost cycles.
Miscellaneous/General:MEK1 is a dual-specificity kinase that phosphorylates ERK1/2, activating it in response to extracellular and intracellular signals. It also acts to downregulate PPAR γ by a direct interaction that results in PPAR γ moving into the cytoplasm from the nucleus.
 

-80°C