GDC-0941
货号: 1623-5 产品名称: GDC-0941 品牌: Biovision 规格: 5 mg 3周到货 生化实验
GDC-0941
Product Overview
Product Name: GDC-0941
Alternate Name/Synonyms: 2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2- d]pyrimidine
Description: GDC-0941 is a potent inhibitor of p110α and p110δ (IC₅₀ = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 957054-30-7
Molecular Formula: C₂₃H₂₇N₇O₃S₂
Molecular Weight: 513.64
Purity: ≥99% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
InChi: InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
InChi Key: LHNIIDJUOCFXAP-UHFFFAOYSA-N
PubChem CID: 17755052
MDL Number: MFCD11616196
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)