Survivin, human recombinant

货号： 4160-50      产品名称： Survivin, human recombinant   品牌： Biovision 规格： 50 μg 3周到货 生化实验

Survivin, human recombinant
An inhibitor of caspase activation/apoptosis
Product Overview
Alternate Names / Synonyms: Survivin, BIRC5; API4; EPR-1
Gene Symbol: BIRC5
Accession #: O15392
Gene ID: 332
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 18.6 kDa
Purity by SDS-PAGE: ≥90%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: N/A
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in PBS.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: Survivin, a member of the inhibitor of apoptosis (IAP) family, is also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5 and in humans is encoded by the BIRC5 gene. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis. Disruption of survivin induction pathways leads to an increase in apoptosis and decrease in tumour growth. Survivin is highly expressed in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells, making survivin an ideal target for studying cancer therapy.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C