BMP-12/GDF-7, human recombinant

货号： 4572-100      产品名称： BMP-12/GDF-7, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

BMP-12/GDF-7, human recombinant
A protein with functions in regulating inflammatory and apoptotic pathways
Product Overview
Alternate Names / Synonyms: BMP-12/GDF-7, BMP12/GDF7, BMP 12/GDF 7,
Gene Symbol: BMP12/GDF7
Accession #: BAD07014
Gene ID: 151449
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized with no additives
Molecular Weight: 27 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The protein is biologically active as determined by its ability to induce alkaline phosphatase production by ADTC5 mouse chondrogenic cells. The ED₅₀ for this effect is typically 0.2 – 2.5 µg/ml.
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C