BMP-11, human recombinant

货号： 4576-50      产品名称： BMP-11, human recombinant   品牌： Biovision 规格： 50 μg 3周到货 生化实验

BMP-11, human recombinant
A protein that controls anterior-posterior patterning by regulating the expression of Hox genes
Product Overview
Alternate Names / Synonyms: bone morphogenetic protein 11, BMP11, BMP 11, Growth/Differentiation Factor-11, GDF-11, GDF11, GDF 11
Gene Symbol: BMP11/GDF11
Accession #: O95390
Gene ID: 10220
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from 10 mM Sodium Citrate, pH 3.5.
Molecular Weight: 32.6 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The protein is biologically active as determined by its ability to induce alkaline phosphatase production by C2C12 cells. The ED₅₀ is in the range of 0.4-4 µg/ml.
Reconstitution Instructions: Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 μg BSA per 1 μg of protein). This solution can then be diluted into other aqueous buffers.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-11 is N-terminus His-tagged protein with a molecular weight of 32.6 kDa (for homodimeric) and 16.2 (for monomeric) consisting of 136 amino acid polypeptide chains.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C