VEGF-D, human recombinant

货号： 4643-1000      产品名称： VEGF-D, human recombinant   品牌： Biovision 规格： 1 mg 3周到货 生化实验

VEGF-D, human recombinant
A protein involved in angiogenesis, lymphangiogenesis and endothelial cell growth and survival
Product Overview
Alternate Names / Synonyms: VEGF-D, VEGF D, VEGF D
Gene Symbol: FIGF
Accession #: O43915
Gene ID: 2277
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized without additives
Molecular Weight: N/A
Purity by SDS-PAGE: ≥98%
Purity by HPLC: N/A
Endotoxin Level: <0.1 ng/μg
Biological Activity: N/A
Reconstitution Instructions: Reconstitute in dH₂O to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: VEGF-D is most closely related to VEGF-C by virtue of the presence of N- and C-terminal extensions that are not found in other VEGF family members. In adult human tissues, VEGF-D mRNA is most abundant in heart, lung, skeletal muscle, colon, and small intestine. Analyses of VEGF-D receptor specificity revealed that VEGF-D is a ligand for both VEGF receptors (VEGFRs) VEGFR-2 (Flk1) and VEGFR-3 (Flt4) and can activate these receptors. However, VEGF-D does not bind to VEGFR-1. Expression of a truncated derivative of VEGF-D demonstrated that the receptor-binding capacities reside in the portion of the molecule that is most closely related in primary structure to other VEGF family members and that corresponds to the mature form of VEGF-C. In addition, VEGF-D is a mitogen for endothelial cells. Recombinant VEGF-D was expressed based on sequence from Genebank Accession# D89630, 20-354 aa.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C