ApoE3, human recombinant

货号： 4696-100      产品名称： ApoE3, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

ApoE3, human recombinant
Apolipoprotein essential for the normal catabolism of triglyceride-rich lipoprotein constituents
Product Overview
Alternate Names / Synonyms: Human ApoE3, ApoE3, Apo-E3, Apo E3, h-ApoE3, rh-ApoE3, recombinant human ApoE3, recombinant human ApoE3, Apo
Gene Symbol: APOE
Accession #: NM_000041
Gene ID: 348
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 20 mM Sodium Phosphate
Molecular Weight: 34 kDa
Purity by SDS-PAGE: ≥90%
Purity by HPLC: ≥90%
Endotoxin Level: <0.1 ng/μg
Biological Activity: Test in process
Reconstitution Instructions: Reconstitute in 5 mM Sodium Phosphate pH 7.8 + 0.5 mM DTT to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. It’s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population. Recombinant human ApoE3 is a 34.0 kDa protein containing 299 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C