ZM 336372

货号： 1789-1      产品名称： ZM 336372   品牌： Biovision 规格： 1 mg 3周到货 生化实验

ZM 336372
A c-Raf kinase inhibitor
Product Overview
Product Name: ZM 336372
Alternate Name/Synonyms: 3-(Dimethylamino)-N-[3-[(4-hydroxybenzoyl)-amino]-4-methylphenyl]benzamide
Description: Cell-permeable. A potent, selective and ATP-competitive inhibitor of c-Raf in vitro (IC₅₀ = 70 nM for inhibition of human c-Raf). Displays 10-fold selectivity over B-Raf. Also inhibits SAPK2/p38 (IC₅₀= 2 μM).
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 208260-29-1
Molecular Formula: C₂₃H₂₃N₃O₃
Molecular Weight: 389.45
Purity: ≥98% by HPLC
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O
InChi: InChI=1S/C23H23N3O3/c1-15-7-10-18(24-23(29)17-5-4-6-19(13-17)26(2)3)14-21(15)25-22(28)16-8-11-20(27)12-9-16/h4-14,27H,1-3H3,(H,24,29)(H,25,28)
InChi Key: PYEFPDQFAZNXLI-UHFFFAOYSA-N
PubChem CID: 5730
MDL Number: MFCD02683971
USAGE: For Research Use Only! Not For Use in Humans.

-20°C