Lithocholic acid

货号： 2187-1G      产品名称： Lithocholic acid   品牌： Biovision 规格： 1 g 3周到货 生化实验

Lithocholic acid
A detergent and an endogenous inhibitor of MDM2 and MDM4
Product Overview
Product Name: Lithocholic acid
Alternate Name/Synonyms: 3α-Hydroxy-5β-cholan-24-oic acid, 3α-Hydroxy-5β-cholanic acid, 5β-Cholan-24-oic acid-3α-ol; LCA
Description: Lithocholic acid (LCA) is a hydrophobic secondary bile acid that is primarily formed in the intestine by the bacterial 7-α dehydroxylation of chenodeoxycholic acid. Acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 binding sites of both MDM2 and MDM4 with a five-fold preference for MDM4.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 434-13-9
Molecular Formula: C₂₄H₄₀O₃
Molecular Weight: 376.57
Purity: ≥97% by TLC
Solubility:DMSO or EtOH
Storage Temp.: RT
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2CCC4C3(CCC(C4)O)C)C
InChi: InChI=1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChi Key: SMEROWZSTRWXGI-HVATVPOCSA-N
PubChem CID: 9903
MDL Number: MFCD00003682
USAGE: For Research Use Only! Not For Use in Humans.

RT