3-Maleimidopropionic acid N-hydroxysuccinimide ester
货号: 4507 产品名称: 3-Maleimidopropionic acid N-hydroxysuccinimide ester 品牌: AAT 规格: 100 mg 二周到货 生化试验
3-Maleimidopropionic acid N-hydroxysuccinimide ester
Cat # 4507
Storage F/D (see storage codes below)
Unit Size 100 mg
MW 266.21
Solvent DMSO
3-Maleimidopropionic acid N-hydroxysuccinimide ester is a non-cleavable and membrane permeable crosslinker. It contains an amine-reactive succinimidyl ester (SE) and a sulfhydryl-reactive maleimide group. NHS esters react with primary amines at pH 7-9 to form stable amide bonds. Maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. The SE group of 3-maleimidopropionic acid N-hydroxysuccinimide ester is reacted with lysine residues on the carrier protein, converting them to reactive maleimides. 3-Maleimidopropionic acid N-hydroxysuccinimide ester is a reagent that is widely used for generating stable maleimide-activated carrier proteins that can spontaneously react with sulfhydryls. Alternatively these relatively stable maleimide-activated intermediates may be lyophilized and stored for later conjugation to a hapten.
Detailed Information: Protocol References MSDS
Related Products: General proteins Amine to Thiol Thiol-Reactive Probes
Storage Codes:
D = Desiccated
L = Avoid light
F = Freeze (<-15 癈)
R = Refrigerated (2-4 癈)
RT = Room temperature (4-50 癈)