ODN 2216 FITC

货号： tlrl-2216f      产品名称： ODN 2216 FITC   品牌： Invivogen 规格： 50 μg 二周到货 生化试验

ODN 2216 FITC
FITC labeled CpG oligonucleotide – Human TLR9 ligand
CpG  ODNs are synthetic oligonucleotides that contain unmethylated CpG  dinucleotides in particular sequence contexts (CpG motifs). These CpG  motifs are present at a 20-fold greater frequency in bacterial DNA  compared to mammalian DNA. They have been shown to induce a coordinated  set of immune responses based on the activation of immune cells  primarily involved in the recognition of these molecules.
ODN  2216 FITC is a A-class CpG ODN specific for human TLR9. ODN 2216 FITC can  be used to evaluate CpG ODN cellular uptake and localization by  confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm)  or flow cytometry.
Specificity: human TLR9 agonist
Working concentration: 10 ng -10 μg/ml
ODN 2216 sequence
5’-ggGGGACGA:TCGTCgggggg-3’ (20 mer)
Note: Bases in capital letters are phosphodiester and those in lower case are phosphorothioate.
Spectral Properties of FITC
Excitation λ max: 495 nm
Emission λ max: 520 nm