Prostaglandin D2-biotin
货号： 10006697-50 产品名称： Prostaglandin D2-biotin 品牌： Cayman 规格： 50 碌g 3周
Prostaglandin D2-biotin
Cayman Chemical Item Number 10006697
Description
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells, certain macrophages, and is the predominant PG in the cerebral spinal fluid. PGD2 inhibits platelet aggregation, induces sleep, causes flushing, vasodilation and nasal congestion, and immune modulation, acting through at least two 7-transmembrant G protein-coupled receptors, DP1 and DP2 (CRTH2). PGD2-biotin is an affinity probe which allows PGD2 to be detected through an interaction with the biotin ligand. It was designed to allow PGD2 to be detected in complexes with transmembrane receptors and/or nucleic acid or protein binding partners. It is thus a tool to be used in the general elucidation of the mechanism of action of PGs.
Synonyms PGD2-biotin
Formal Name 9α,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oyl-N’-biotinoyl-1,5-diaminopentane
Molecular Formula C36H60N4O6S
Formula Weight 677.0
Formulation A solution in ethanol
Purity >95%
Stability 1 year
Storage -20°C
Shipping Wet ice in continental US; may vary elsewhere
SMILES O=C1C[C@H](O)[C@H](C/C=CCCCCC(NCCCCCNC(CCCC[C@@H]2SC[C@@](N3)([H])[C@]2([H])NC3=O)=O)=O)[C@H]1/C=C/[C@@H](O)CCCCC
InCHI Code 1S/C36H60N4O6S/c1-2-3-8-15-26(41)20-21-28-27(30(42)24-31(28)43)16-9-5-4-6-10-18-33(44)37-22-13-7-14-23-38-34(45)19-12-11-17-32-35-29(25-47-32)39-36(46)40-35/h5,9,20-21,26-30,32,35,41-42H,2-4,6-8,10-19,22-25H2,1H3,(H,37,44)(H,38,45)(H2,39,40,46)
InCHI Key OIOFLLOCLYRSFU-WDPYDZKRSA-N
-20°C
