Anti-SG2NA (mouse monoclonal)
货号： 05-1115 产品名称： Anti-SG2NA (mouse monoclonal) 品牌： Millipore 规格： EA 3周到货 生化实验
Anti-SG2NA Antibody
Recommended Replacement for: 05-1115 is a recommended replacement for MAB5464
Species Reactivity Key Applications Host Format Antibody Type
H, R, M WB, ICC, IP Mouse Ascites Monoclonal Antibody
Description:
Anti-SG2NA Antibody
Replaces:
05-1115 is a recommended replacement for MAB5464
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Specificity:
Reacts with SG2NA. No cross reactivity with striatin.
Molecular Weight:
The antibody recognizes the ~93 kDa SG2NA protein in Jurkat cell lysate. In some cell types a band of ~70 kDa is also recognized, which may be an alternatively spliced form of SG2NA or another unknown protein.
Immunogen:
Synthetic peptide from SG2NA.
Isotype:
IgG1
Background Information:
SG2NA, also known as Striatin 3, was identified as a human cancer auto-antigen and has not been implicated in vesicular trafficking and signal tranduction. It is highly related to striatin and zinedin (striatin 4). It is a cytoplasmic scaffolding protein that binds to Calmodulin and PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which appears to modulate PP2A activity.
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Species Reactivity:
Human
Rat
Mouse
Species Reactivity Note:
Human, Rat and Mouse.
Application Notes:
Immunocytochemistry: A previous lot of this antibody was used in immunocytochemistry at a 1:500 dilution.
Immunoprecipitation: A previous lot of this antibody was used in IP; 3 μL is a recommended as starting point for immunoprecipitation.
Optimal working dilutions must be determined by end user.
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Control:
L6 cell lysate
Quality Assurance:
Routinely evaluated by Western Blot on L6 lysates.
Western Blot Analysis: 1:500 dilution of this lot detected SG2NA on 10 μg of L6 lysates.
Presentation:
Mouse monoclonal IgG1 ascites containing 40% glycerol and 0.02% sodium azide.
Storage Conditions:
Stable at -20°C in undiluted aliquots for up to 1 year from date of receipt. For long-term storage, may be stored at -80°C.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
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UniProt Number:
Q13033
Entrez Gene Number:
NM_001083893.1
Gene Symbol:
STRN3
Striatin-3
GS2NA
SG2NA
Alternate Names:
Cell-cycle autoantigen SG2NA
Striatin 3
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunocytochemistry
Immunoprecipitation
UniProt Summary:
FUNCTION: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
SUBUNIT: Interacts with protein phosphatase 2A (PP2A) (Potential).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).
ALTERNATIVE PRODUCTS: 2 named isoforms [FASTA] produced by alternative splicing. Additional isoforms seem to exist. Name Beta
Isoform ID Q13033-1
This is the isoform sequence displayed in this ent -20°C
